Agarotetrol

CAS# 69809-22-9

Agarotetrol

Catalog No. BCN6763----Order now to get a substantial discount!

Product Name & Size Price Stock
Agarotetrol: 5mg $104 In Stock
Agarotetrol: 10mg Please Inquire In Stock
Agarotetrol: 20mg Please Inquire Please Inquire
Agarotetrol: 50mg Please Inquire Please Inquire
Agarotetrol: 100mg Please Inquire Please Inquire
Agarotetrol: 200mg Please Inquire Please Inquire
Agarotetrol: 500mg Please Inquire Please Inquire
Agarotetrol: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of Agarotetrol

Number of papers citing our products

Chemical structure

Agarotetrol

3D structure

Chemical Properties of Agarotetrol

Cas No. 69809-22-9 SDF Download SDF
PubChem ID 13606036 Appearance Powder
Formula C17H18O6 M.Wt 318.3
Type of Compound Phenols Storage Desiccate at -20°C
Solubility DMSO : ≥ 250 mg/mL (785.37 mM)
*"≥" means soluble, but saturation unknown.
Chemical Name (5S,6R,7R,8S)-5,6,7,8-tetrahydroxy-2-(2-phenylethyl)-5,6,7,8-tetrahydrochromen-4-one
SMILES C1=CC=C(C=C1)CCC2=CC(=O)C3=C(O2)C(C(C(C3O)O)O)O
Standard InChIKey CWMIROLCTHMEEO-JJXSEGSLSA-N
Standard InChI InChI=1S/C17H18O6/c18-11-8-10(7-6-9-4-2-1-3-5-9)23-17-12(11)13(19)14(20)15(21)16(17)22/h1-5,8,13-16,19-22H,6-7H2/t13-,14+,15+,16-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Agarotetrol

The herbs of Aquilaria sinensis

Biological Activity of Agarotetrol

DescriptionAgarotetrol is a chromone derivative isolated from Agarwood.

Protocol of Agarotetrol

Structure Identification
Chemical & Pharmaceutical Bulletin, 2008 , 34 (7) :3033-7.

Studies on the Agalwood (Jinko). VI. : Structures of Three 2-(2-Phenylethyl)-5,6,7,8-tetrahydrochromone Derivatives, AH_<1A>, AH_<2a> and AH_<2b>[Reference: WebLink]

Three new kinds of phenylethyl chromone derivatives, named AH_<1A>, AH_<2a> and AH_<2b>, were isolated from the crude AH_1 (Agarotetrol) and AH_2 (isoAgarotetrol) fractions of agalwood (Jinko)from Kalimantan. AH<1A> separated from the crude AH_1 fraction through the process of acetylation was characterized as 2-[2-(4-methoxyphenyl)ethyl]-5α, 6β, 7β, 8α-tetraacetoxy-5,6,7,8-tetrahydro-chromone, and AH_<2a> and AH<2b>, from crude AH_2 fraction, were established to be 2[2-(4-methoxyphenyl)ethyl]- and 2-[2-(2-hydroxyphenyl)ethyl]-5α, 6β, 7α, 8β-tetrahydroxy-5,6,7,8-tetrahydrochromone, respectively.

Agarotetrol Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Agarotetrol Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Agarotetrol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1417 mL 15.7085 mL 31.4169 mL 62.8338 mL 78.5423 mL
5 mM 0.6283 mL 3.1417 mL 6.2834 mL 12.5668 mL 15.7085 mL
10 mM 0.3142 mL 1.5708 mL 3.1417 mL 6.2834 mL 7.8542 mL
50 mM 0.0628 mL 0.3142 mL 0.6283 mL 1.2567 mL 1.5708 mL
100 mM 0.0314 mL 0.1571 mL 0.3142 mL 0.6283 mL 0.7854 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Agarotetrol

Three new 5,6,7,8-tetrahydroxy-5,6,7,8-tetrahydrochromone derivatives enantiomeric to agarotetrol from agarwood.[Pubmed:29525833]

J Nat Med. 2018 Jun;72(3):667-674.

Agarwood (jinkoh in Japanese) is a resinous wood from Aquilaria species of the family Thymelaeaceae and has been used as incense and in traditional medicines. Characteristic chromone derivatives such as Agarotetrol have been isolated from agarwood. In previous study, we isolated two new 2-(2-phenylethyl)chromones together with six known compounds from MeOH extract of agarwood. Further chemical investigation of the MeOH extract led to isolation of eighteen 2-(2-phenylethyl)chromones, including three new 5,6,7,8-tetrahydroxy-5,6,7,8-tetrahydrochromones with stereochemistry enantiomeric to Agarotetrol-type, viz. (5R,6S,7S,8R)-2-[2-(3'-hydroxy-4'-methoxyphenyl)ethyl]-5,6,7,8-tetrahydroxy-5,6,7 ,8-tetrahydrochromone (2), (5R,6S,7S,8R)-2-[2-(4'-methoxyphenyl)ethyl]-5,6,7,8-tetrahydroxy-5,6,7,8-tetrahyd rochromone (6), and (5R,6S,7S,8R)-2-[2-(4'-hydroxy-3'- methoxyphenyl)ethyl]-5,6,7,8-tetrahydroxy-5,6,7,8-tetrahydrochromone (13). The absolute configurations of the new compounds were determined by exciton chirality method. All isolated compounds were tested for their phosphodiesterase (PDE) 3A inhibitory activity by fluorescence polarization method. Compounds 8, 12-15, 21-24 showed moderate PDE 3A inhibitory activity.

Agarotetrol: a source compound for low molecular weight aromatic compounds from agarwood heating.[Pubmed:29464509]

J Nat Med. 2018 Mar;72(2):537-541.

Agarwood is known to generate a distinct fragrance upon heating and is used as both a medicine and a fragrant wood. Low molecular weight aromatic compounds (LACs) such as benzylacetone are emitted from agarwood on heating and have a sedative effect on mice. These are detected exclusively in the headspace vapor of heated agarwood and are absent in the wood itself; hence, some compounds in agarwood are thought to be converted to LACs by the process of heating. In this study, different fractions obtained from agarwood were analyzed to reveal the source compounds of LACs. Some LACs detected in the resinous agarwood were absent from the non-resinous parts and confirmed as characteristic of the resinous parts. The essential oil and hydrosol of agarwood obtained by distillation were analyzed by gas chromatography-mass spectrometry (GC-MS). Sesquiterpenes were detected in the essential oil, and sesquiterpenes and a variety of LACs were detected in the hydrosol. A hot water extract of agarwood remaining in the distillation flask after distillation was analyzed by high-performance liquid chromatography (HPLC), and Agarotetrol was found to be the main compound. Purified Agarotetrol was heated in a glass vial and its headspace vapor was analyzed by solid-phase microextraction GC-MS. Benzylacetone and other LACs were detected. These results indicate that Agarotetrol, a chromone derivative, contributes to the fragrance of agarwood through the generation of LACs upon heating.

Description

Agarotetrol is a chromone derivative isolated from Agarwood.

Keywords:

Agarotetrol,69809-22-9,Natural Products, buy Agarotetrol , Agarotetrol supplier , purchase Agarotetrol , Agarotetrol cost , Agarotetrol manufacturer , order Agarotetrol , high purity Agarotetrol

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: