Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8902 | (E)-6-O-(p-coumaroyl)scandoside methyl ester |
| (E)-6-O-(p-coumaroyl)scandoside methyl ester shows moderate anti-proliferation effect on PC3 human androgen-independent prostate cancer cells. | |
| BCN8910 | Biatractylolide |
| Biatractylolide has a neuroprotective effect on glutamate-induced injury in PC12 and SH-SY5Y cells through a mechanism of the PI3K-Akt-GSK3β-dependent pathways. The molecular mechanisms of inhibitory activities of biatractylolide on AChE are not only through binding to AChE, but also via reducing AChE expression by inhibiting the activity of GSK3β. | |
| BCN8914 | Methylgomisin O |
| Methylgomisin O has anti- inflammatory activity, it -induced attenuation of inflammatory cytokine production upon exposure to LPS was at least partially mediated by the suppression of NF-κB and MAPK pathway. Methylgomisin O exhibits strong cytotoxic effects on HL-60. It exhibits considerable inhibitory activity against tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6). | |
| BCN8917 | Licoflavanone |
| Licoflavanone exhibits antioxidant and anti-inflammatory activities,it markedly decreases pro-inflammatory cytokines and cyclooxygenase 2/inducible nitric oxide synthase (COX-2/iNOS) expression levels. | |
| BCN8920 | Ginsenoside MC |
| Ginsenoside MC exhibits potent antitumor activity. Ginsenoside MC has improving anti-aging, anti-acne, anti-inflammatory, anti-microbial and moisturizing effects and promoting hair growth and anti-dandruff effect. | |
| BCN8923 | (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol |
| (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol has anti-oomycete potential. | |
| BCN8925 | Nardoaristolone B |
| Nardoaristolone B, a nor-sesquiterpenoid with an unusual fused ring system and having protective effects on the injury of neonatal rat cardiomyocytes. The novel mosquito-repellentsynthetic hydrindanesbased on noreremophilanes and nardoaristolone B which show increasedactivity against adult females of Aedes aegypti. | |
| BCN8773 | Citrusin B |
| Citrusin B exhibits moderate in vitro inhibitory effect on tobacco mosaic virus replication with IC₅₀ values 0.26 mmol L⁻1. | |
