Oleaside A

CAS# 69686-84-6

Oleaside A

Catalog No. BCN6772----Order now to get a substantial discount!

Product Name & Size Price Stock
Oleaside A: 5mg $219 In Stock
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Quality Control of Oleaside A

Number of papers citing our products

Chemical structure

Oleaside A

3D structure

Chemical Properties of Oleaside A

Cas No. 69686-84-6 SDF Download SDF
PubChem ID 5458792 Appearance Powder
Formula C30H44O7 M.Wt 516.7
Type of Compound Steroids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1C(C(CC(O1)OC2CCC3(C(C2)CCC45C3CCC(C4=O)(C(CC5)C6=CC(=O)OC6)C)C)OC)O
Standard InChIKey DFDVWAJDFYYBAC-BVCCMOTMSA-N
Standard InChI InChI=1S/C30H44O7/c1-17-26(32)22(34-4)15-25(36-17)37-20-6-9-28(2)19(14-20)5-11-30-12-7-21(18-13-24(31)35-16-18)29(3,27(30)33)10-8-23(28)30/h13,17,19-23,25-26,32H,5-12,14-16H2,1-4H3/t17?,19-,20+,21-,22?,23-,25?,26?,28+,29-,30-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Oleaside A

The herbs of Nerium oleander

Biological Activity of Oleaside A

DescriptionOleaside A is a natural product from Nerium oleander.
In vitro

Biotransformation of Oleaside A by Cunninghamella echinulata.[Reference: WebLink]

Helvetica Chimica Acta, 2014 , 97 (2) :290-7.

Biotransformation of Oleaside A (1) by Cunninghamella echinulata (ACCC 30369) was carried out to afford two products, (6R)‐6‐hydroxyOleaside A (2) and (7S)‐7‐hydroxyOleaside A (3).
METHODS AND RESULTS:
The structures of 2 and 3 were elucidated by extensive NMR analyses and further confirmed by single‐crystal X‐ray diffraction analysis. We also report herein the X‐ray diffraction structure of Oleaside A (1) for the first time. Compounds 1–3 were evaluated for their cytotoxic activities against the A549, HCT116, HepG2, and HL‐60 human cancer cell lines.

Quantitative variations in the cardiac glycosides of oleander.[Reference: WebLink]

Phytochemistry,1983 ,22(10) :2211-4.


METHODS AND RESULTS:
Cardiac glycosides of the leaves from 20 horticultural and wild strains of Nerium were examined quantitatively. The plants investigated fall into two groups based on their contents of adynerin and Oleaside A, or gentiobiosyl adynerin and oleaside E.
CONCLUSIONS:
A large variation in oleandrin content was noted in all samples.

Oleaside A Dilution Calculator

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Oleaside A Molarity Calculator

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Preparing Stock Solutions of Oleaside A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9354 mL 9.6768 mL 19.3536 mL 38.7072 mL 48.384 mL
5 mM 0.3871 mL 1.9354 mL 3.8707 mL 7.7414 mL 9.6768 mL
10 mM 0.1935 mL 0.9677 mL 1.9354 mL 3.8707 mL 4.8384 mL
50 mM 0.0387 mL 0.1935 mL 0.3871 mL 0.7741 mL 0.9677 mL
100 mM 0.0194 mL 0.0968 mL 0.1935 mL 0.3871 mL 0.4838 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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