Hot Natural Products & Bioactive Compounds
BioCrick offers high-purity natural products and bioactive compounds for scientific research. Our natural product collection includes compounds derived from plants, microorganisms and other biological sources and is widely used in pharmacological, biochemical and drug discovery research.
Natural products remain an important source of bioactive molecules and drug leads. BioCrick provides researchers with high-quality natural product compounds together with catalog numbers, product information and biological activity data.
Hot Products from BioCrick
Showing 3729 - 3736 of 9359 hot products
| Catalog No. | Product Name |
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| BCN1181 | 2-Deacetoxytaxinine B |
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1. 2-Deacetoxytaxinine B is a strongly inhibitor against U46619-induced aggregation.
2. 2-Deacetoxytaxinine B shows strong inhibitory effects against arachidonic acid (AA)-induced aggregation. |
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| BCN1182 | Deoxypodophyllotoxin |
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Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities. Deoxypodophyllotoxin induces G2 /M cell-cycle arrest followed by apoptosis through multiple cellular processes, involving the activation of ATM, upregulation of p53 and Bax, activation of caspase-3 and -7, and accumulation of PTEN resulting in the inhibition of the Akt pathway. Deoxypodophyllotoxin maybe applicable to treat hyperpigmentation, it decreases UV-induced skin pigmentation of brown guinea pigs.
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| BCN1183 | Ergosta-4,6,8(14),22-tetraen-3-one |
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1. Ergosta-4,6,8(14),22-tetraen-3-one can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of many medicinal fungi in cancer treatment.
2. Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell. 3. Ergosta-4,6,8(14),22-tetraen-3-one treatment can confer protection against early renal injury in a rat model of aristolochic acid (AA) nephropathy, early administration of it may prevent the progression of renal injury and the subsequent renal fibrosis in AA nephropathy. 4. Ergosta-4,6,8(14),22-tetraen-3-one has inhibitory activity of nitric oxide production in RAW 264.7 cells stimulated by lipopolysaccharide was examined and shows a potential activity with the IC(50) value of 28.96 microM. |
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| BCN1184 | Cardamonin |
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Cardamonin is a naturally occurring chalcone with strong anti-inflammatory , anticancer, anti-melanogenesis, and vascular activity. It is a novel TRPA1 antagonist with IC50 of 454 nM and also a NF-kB inhibitor. It ameliorates insulin resistance induced by high insulin and high glucose through the mTOR and signal pathway. It also may be a potential whitening agent for use in cosmetics and in the medical treatment of hyperpigmentation disorders.
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| BCN1185 | 10-O-Vanilloylaucubin |
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1. 10-O-Vanilloylaucubin shows significant writhing inhibition following oral administration at doses of 25 mg/kg.suggests that it has analgesic effects.
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| BCN1186 | Rivulobirin B |
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Rivulobirin B is a natural product from Heracleum rapula Franch.
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| BCN1187 | Isohyenanchin |
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1. Isohyenanchin is a weak antagonist of ionotropic GABA receptors.
2. Isohyenanchin is the potent antagonist of RDLac homo-oligomers. |
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| BCN1188 | 4-Hydroxycinnamamide |
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1. 4-Hydroxycinnamamide has antioxidant activity.
2. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases. |
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