Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN5778 | Stigmast-4-ene-3,6-dione |
| 1. Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties. | |
| BCN5779 | Carpachromene |
| 1. Carpachromene blocks protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-stimulated macrophages, it could be a potential anti-inflammatory agent. 2. Carpachromene exhibits significant cytotoxicity against HepG2, PLC/PRF/5 and Raji cancer cell lines in vitro. 3. Carpachromene shows significant α-glucosidase inhibitory activity. | |
| BCN5780 | Sucrose |
| Sucrose is used extensively as a food and a sweetener, it is the most efficient large-scale crop capable of supplying sufficient carbon substrate, in the form of Sucrose, needed during fermentative feedstock production. | |
| BCN5781 | Isofuranodiene |
| 1. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apoptosis in cancer cells. 2. Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. 3. Isofuranodiene can induce apoptosis in colon cancer cells in a time and concentration-dependent manner suggesting a potential role as models for the development of chemopreventive agents. 4. Isofuranodiene at concentrations of 25 and 12.5 lM alone, or in combination with 50 nM nerve growth factor (NGF) , shows a marked stimulation of neuritogenesis,which appears to be a promising neurotrophic and neuroprotective agent. | |
| BCN5782 | (3beta,24xi)-Cycloartane-3,24,25-triol |
| 1. Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. 2. Cycloartane-3,24,25-triol reduces the viability of PC-3 and DU145 cell lines with IC50 values of 2.226 ± 0.28 μM and 1.67 ± 0.18 μM respectively. | |
| BCN5786 | 2-Acetylbenzoic acid |
| 2-Acetylbenzoic acid is more potent than 2-propionyloxybenzoic acid in inhibiting platelet function and platelet prostaglandin (PG) synthesis although the potencies of these agents were comparable in inhibiting prostacyclin (PGI2) synthesis. | |
| BCN5787 | Ergosterol |
| Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects, ergosterol peroxide has the potential to be developed as a therapeutic agent to prevent renal fibrosis. Ergosterol can promote pheromone signaling and plasma membrane fusion in mating yeast, the critical requirement for ergosterol in V-ATPase function may underlie the antifungal activity of azoles. | |
| BCN5788 | Cosmosiin |
| Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. | |
