Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN5712 Onitin
1. Onitin shows super-oxide and DPPH free radical scavenging effects. 2. Onitin exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.
BCN5713 Onitisin
1. Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
BCN5716 Corylin
Corylin has a variety of pharmacological effects such as antioxidant, anti-proliferation, and anti-inflammatory properties, it may stimulate bone formation or have potential activity against osteoporosis. Corylin shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells.
BCN5717 Aristolactam BII
1. Aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells by directly inhibiting the production of nitric oxide. 2. Aristolactam BII exhibits antimicrobial and antiinflammatory activity. 3. Aristolactam BII shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom.
BCN5718 Aristolactam BIII
1. Aristolactam BIII has moderate antitumor activity in selected cell lines. 2. Aristolactam BIII possesses anti-platelet aggregation activity in vitro, it also shows significant cytotoxic activity (IC50 values < 4 microg/mL) against P-388, HT-29 and A549 cell lines in vitro.
BCN5719 Isoastilbin
Isoastilbin has anti-acne and tyrosinase inhibition properties.Isoastilbin, neoastilbin, astilbin and taxifolin have antimicrobial activities, they depress the growth of Streptococcus sobrinus (S. sobrinus) over a concentration range of 9.32-42.7 ug/ml and show GTase inhibitory activity with IC50 values in the range 27.4-57.3 ug/ml.
BCN5720 15-Hydroxydehydroabietic acid
1. 15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities.
BCN5721 Decarine
1. Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages. 2. Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.