BCN3900MoschamineBotanical source: The herbs of Datura stramonium Linn.(CAS NO.:68573-23-9)
BCN4244PrometaphanineBotanical source: The root of Stephania japonica(CAS NO.:6858-85-1)
BCN3466IsorhyncophyllineIsorhynchophylline (IRN), an alkaloid isolated from Uncaria rhynchophylla, possesses the effects of lowered blood pressure, vasodilatation and protection against ischemia-induced neuronal damage.(CAS NO.:6859-01-4)
BCN6458IsorhynchophyllineBotanical source: The stem with hook of Uncaria rhynchophylla.(CAS NO.:6859-1-4)
BCN7076AsimilobineBotanical source: The stems and leaves of Fissistigma oldhamii.(CAS NO.:6871-21-2)
BCN4245EchitamineBotanical source: The herbs of Alstonia scholaris(CAS NO.:6871-44-9)
BCN8443(-)-LotusineLotusine is a pure alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn. Lotusine shows effects on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers.(CAS NO.:6871-67-6)
BCN4246XanthoplanineXanthoplanine, isolated from theroot of Xylopia parviflora, fully inhibits the EC50 ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC50 values of 9 μM (alpha7) and 5 μM (alpha4beta2).(CAS NO.:6872-88-4)
BCN5387EpiberberineEpiberberine is an alkaloid isolated from Coptis chinensis, acts as a potent AChE and BChE inhibitor, and a non-competitive BACE1 inhibitor, with IC50s of 1.07, 6.03 and 8.55 μM, respectively. Epiberberine has antioxidant activity, with peroxynitrite ONOO- scavenging effect (IC50, 16.83 μM), and may protect against Alzheimer disease. Epiberberine inhibits the early stage of differentiation of 3T3-L1 preadipocytes, downregulates the Raf/MEK1/2/ERK1/2 and AMPKα/Akt pathways. Epiberberine has the potential effect in the research of diabetic disease.(CAS NO.:6873-09-2)
BCN5933PhellodendrinePhellodendrine, a isoquinoline alkaloid, is one of important characteristic ingredients in the Phellodendri chinensis cortex. phellodendrine is against AAPH-induced oxidative stress through regulating the AKT/NF-κB pathway. Phellodendrine has good antioxidant, and anti-inflammatory effect .(CAS NO.:6873-13-8)
BCN7480ArborineArborine, isolated from Glycosmis arborea, inhibits the peripheral action of acetylcholine and induces a fall in blood pressure.(CAS NO.:6873-15-0)
BCN4758VellosimineBotanical source: The herbs of Rauvolfia verticillata(CAS NO.:6874-98-2)
BCN2364CorynoxineCorynoxine is an enantiomer of Corynoxine B; induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.(CAS NO.:6877-32-3)
BCN4986TuberstemonineTuberstemonine, an alkaloid, is an antimalarial agent that targets Plasmodium falciparum ferredoxin-NADP+ reductases (pfFNR).(CAS NO.:6879-01-2)
BCN4811NorfluorocurarineBotanical source: The herbs of Alstonia yunnanensis(CAS NO.:6880-54-2)
BCN2273DihydrochelerythrineDihydrochelerythrine is a natural compound isolated from the leaves of Macleaya microcarpa; has antifungal activity.(CAS NO.:6880-91-7)
BCN4249SophoridineSophoridine is a quinolizidine alkaloid isolated from leafs of Leguminous plant Sophora alopecuroides.L. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor drug candidate for pancreatic cancer with well-tolerated toxicity.(CAS NO.:6882-68-4)
BCN4250SempervirineBotanical source: The herbs of Gelsemium elegans(CAS NO.:6882-99-1)
BCN2009OtonecineBotanical source: The herb of Aster smithianus(CAS NO.:6887-34-9)
BCN7767Uncarine ABotanical source: The leaves of Uncaria hirsuta.(CAS NO.:6899-73-6)
BCN5988HypaconitineHypaconitine, an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism.(CAS NO.:6900-87-4)
