BCN8691Beta-HydroxyisovalerylshikoninBeta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermium radix, acts as a potent inhibitor of protein tyrosine kinases (PTK), with IC50s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells.(CAS NO.:7415-78-3)
BCN8862Isoarnebin Iβ,β-Dimethylacrylshikonin is a naphthoquinone derivative isolated from Arnebia nobilis, promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Arnebin 1 has anti-tumor activity.(CAS NO.:24502-79-2)
BCN8887IsovalerylshikoninBotanical source: The roots of Lithosperraum erythrorhizon Sieb. et Zucc.(CAS NO.:52387-14-1)