Camptotheca acuminata Decne.
Camptotheca acuminata Decne.
Camptotheca acuminata is a member of the family Nyssaceae (tupelo family) and is native only to China and Tibet, where it is known as xi shu. They are usually included in the tupelo family Nyssaceae, but sometimes included (with the tupelos) in the dogwood family Cornaceae. Camptotheca is used to make Irinotecan, Topotecan, 9-Aminocamptothecin, and camptothecin-1 (CPT-1). It also contains trifolin and hyperoside. Camptothecin and these analogs are being investigated to treat a wide variety of cancers, but the compounds are quite toxic, and only topotecan (Hycamtin) and irinotecan HCl (Camptosar) have met with FDA approval; Hycamtin has been approved for ovarian cancer theray, and Camptosar is approved for metastatic colorectal cancers. Some minor constituents, eight ellagic acids and syringic acid, were isolated from the fruits of Camptotheca acuminata Decne. Containing camptothecine,10-hydroxy-camptothecine, meth- oxycamptothecine, etc.
Products from Camptotheca acuminata Decne.
- Cat.No. Product Name CAS Number COA
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BCN4318
Camptothecin 7689-03-4
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BCN1219
9-Methoxycamptothecine 39026-92-1
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BCN1225
(S)-10-Hydroxycamptothecin 19685-09-7
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BCN1226
10-Hydroxycamptothecin 64439-81-2
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BCN2303
10-Methoxycamptothecin 19685-10-0
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BCN5524
Betulinic acid 472-15-1
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BCN1255
Catharanthine 2468-21-5
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BCN5411
Vincristine 57-22-7
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BCN2292
Vinblastine Sulfate 143-67-9
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BCN2376
Vinblastine 865-21-4
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BCN2604
Topotecan hydrochloride 119413-54-6
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BCN2949
Irinotecan hydrochloride 100286-90-6
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BCN1638
2,3,23-Trihydroxy-12-oleanen-28-oic acid 102519-34-6
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BCN2581
10-Nitro-camptothecin 104195-61-1
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BCN2480
7-Ethylcamptothecin 78287-27-1
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BCN2479
7-Ethyl-10-Hydroxycamptothecin 86639-52-3
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BCN2453
9-Aminocamptothecin 91421-43-1
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