Home >> Research Area >>Natural Products>>Alkaloids>> 1-Hydroxyacridone

1-Hydroxyacridone

CAS# 65582-54-9

1-Hydroxyacridone

Catalog No. BCN7524----Order now to get a substantial discount!

Product Name & Size Price Stock
1-Hydroxyacridone: 5mg $725 In Stock
1-Hydroxyacridone: 10mg Please Inquire In Stock
1-Hydroxyacridone: 20mg Please Inquire Please Inquire
1-Hydroxyacridone: 50mg Please Inquire Please Inquire
1-Hydroxyacridone: 100mg Please Inquire Please Inquire
1-Hydroxyacridone: 200mg Please Inquire Please Inquire
1-Hydroxyacridone: 500mg Please Inquire Please Inquire
1-Hydroxyacridone: 1000mg Please Inquire Please Inquire

Quality Control of 1-Hydroxyacridone

Number of papers citing our products

Chemical structure

1-Hydroxyacridone

3D structure

Chemical Properties of 1-Hydroxyacridone

Cas No. 65582-54-9 SDF Download SDF
PubChem ID 10899903 Appearance Powder
Formula C13H9NO2 M.Wt 211.22
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-hydroxy-10H-acridin-9-one
SMILES C1=CC=C2C(=C1)C(=O)C3=C(N2)C=CC=C3O
Standard InChIKey YZTFXTYKRHQLIU-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H9NO2/c15-11-7-3-6-10-12(11)13(16)8-4-1-2-5-9(8)14-10/h1-7,15H,(H,14,16)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 1-Hydroxyacridone

The

Biological Activity of 1-Hydroxyacridone

Description1. 1-Hydroxyacridone has potential antiviral activity.
TargetsHSV

1-Hydroxyacridone Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

1-Hydroxyacridone Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 1-Hydroxyacridone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7344 mL 23.672 mL 47.344 mL 94.688 mL 118.36 mL
5 mM 0.9469 mL 4.7344 mL 9.4688 mL 18.9376 mL 23.672 mL
10 mM 0.4734 mL 2.3672 mL 4.7344 mL 9.4688 mL 11.836 mL
50 mM 0.0947 mL 0.4734 mL 0.9469 mL 1.8938 mL 2.3672 mL
100 mM 0.0473 mL 0.2367 mL 0.4734 mL 0.9469 mL 1.1836 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 1-Hydroxyacridone

SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series.[Pubmed:17937990]

Bioorg Med Chem. 2008 Jan 1;16(1):313-21.

Herpes Simplex Virus (HSV) infections are among the most common human diseases. In this work, we assess the structural features and electronic properties of a series of ten 1-Hydroxyacridone derivatives (1a-j) recently described as a new class of non-nucleoside inhibitors of Herpes Simplex Virus-1 (HSV-1). Based on these molecules, we applied rigid analogue and isosteric replacement approaches to design and synthesize nine new 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine derivatives (2a-i). The biological and computational results of these new molecules were compared with 1-Hydroxyacridones. An inhibitory profile was observed in 10-Cl substituted 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine derivative (2f), which presents the same substituent at the analogous position of 1-Hydroxyacridone derivative (1b). The structure-activity relationship (SAR) studies pointed out the 10-position next to nitrogen atom as important for the anti-HSV-1 profile in the pyrazolo-naphthyridine derivatives tested, which reinforced the promising profile for further experimental investigation. The most potent acridone and pyrazolo-naphthridine derivatives were also submitted to an in silico ADMET screening in order to determine their overall drug-score, which confirmed their potential antiviral profile.

Keywords:

1-Hydroxyacridone,65582-54-9,Natural Products, buy 1-Hydroxyacridone , 1-Hydroxyacridone supplier , purchase 1-Hydroxyacridone , 1-Hydroxyacridone cost , 1-Hydroxyacridone manufacturer , order 1-Hydroxyacridone , high purity 1-Hydroxyacridone

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: