11,12-De(methylenedioxy)danuphyllineCAS# 888482-17-5 |
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| Cas No. | 888482-17-5 | SDF | Download SDF |
| PubChem ID | 91885229 | Appearance | Cryst. |
| Formula | C23H26N2O6 | M.Wt | 426.5 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | COC(=O)C12CCC34CCCN(C3C1(CC(=O)C4)C5=CC=CC=C5N2C(=O)OC)C=O | ||
| Standard InChIKey | OMANQXKGUWJXTD-JBJBFBLISA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The branch of Kopsia officinalis
| Description | Standard reference |
| In vitro | Three New Indole Alkaloids from the Leaves of Kopsia officinalis.[Reference: WebLink]Helvetica Chimica Acta.2006 March;89(3):515–519.
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11,12-De(methylenedioxy)danuphylline Dilution Calculator
11,12-De(methylenedioxy)danuphylline Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3447 mL | 11.7233 mL | 23.4467 mL | 46.8933 mL | 58.6166 mL |
| 5 mM | 0.4689 mL | 2.3447 mL | 4.6893 mL | 9.3787 mL | 11.7233 mL |
| 10 mM | 0.2345 mL | 1.1723 mL | 2.3447 mL | 4.6893 mL | 5.8617 mL |
| 50 mM | 0.0469 mL | 0.2345 mL | 0.4689 mL | 0.9379 mL | 1.1723 mL |
| 100 mM | 0.0234 mL | 0.1172 mL | 0.2345 mL | 0.4689 mL | 0.5862 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Three New Indole Alkaloids from the Leaves of Kopsia officinalis.
Helvetica Chimica Acta.2006 March;89(3):515–519.
Three new indole alkaloids, 11,12-De(methylenedioxy)danuphylline (1), methyl (2β,11β,12β,19α)-6,7-didehydro-8,21-dioxo-11,21-cycloaspidospermidine-2-carboxylate (2), and (2β,5β)-aspidofractinin-16-ol (3) were isolated from Kopsia officinalis, together with 16 known compounds. Their structures were determined by spectroscopic methods. The isolated known compound (−)-12-methoxykopsinaline displayed antimanic effects in Drosophila, with an IC50 value of 12.5 μg/ml.
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