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Gaudichaudic acid

CAS# 887923-46-8

Gaudichaudic acid

2D Structure

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Quality Control of Gaudichaudic acid

3D structure

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Gaudichaudic acid

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Chemical Properties of Gaudichaudic acid

Cas No. 887923-46-8 SDF Download SDF
PubChem ID 102004808 Appearance Powder
Formula C33H38O8 M.Wt 562.7
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(=CCC1=C(C2=C(C(=C1O)CC=C(C)C)OC34C5CC(C=C3C2=O)C(=O)C4(OC5(C)C)CC=C(C)C(=O)O)O)C
Standard InChIKey AGLFUQQNMWKHEY-HMUZKCJLSA-N
Standard InChI InChI=1S/C33H38O8/c1-16(2)8-10-20-25(34)21(11-9-17(3)4)28-24(26(20)35)27(36)22-14-19-15-23-31(6,7)41-32(29(19)37,33(22,23)40-28)13-12-18(5)30(38)39/h8-9,12,14,19,23,34-35H,10-11,13,15H2,1-7H3,(H,38,39)/b18-12-/t19-,23?,32?,33-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Gaudichaudic acid

The herbs of Garcinia hanburyi Hook. f.

Biological Activity of Gaudichaudic acid

Description1. Gaudichaudic acid shows cytotoxicities against human leukemia K562 (K562/S) and doxorubicin-resistant K562 (K562/R) cell lines, and shows similar inhibitory effects on both cell lines.

Gaudichaudic acid Dilution Calculator

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Gaudichaudic acid Molarity Calculator

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Preparing Stock Solutions of Gaudichaudic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7771 mL 8.8857 mL 17.7715 mL 35.5429 mL 44.4286 mL
5 mM 0.3554 mL 1.7771 mL 3.5543 mL 7.1086 mL 8.8857 mL
10 mM 0.1777 mL 0.8886 mL 1.7771 mL 3.5543 mL 4.4429 mL
50 mM 0.0355 mL 0.1777 mL 0.3554 mL 0.7109 mL 0.8886 mL
100 mM 0.0178 mL 0.0889 mL 0.1777 mL 0.3554 mL 0.4443 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Gaudichaudic acid

Cytotoxic polyprenylated xanthones from the resin of Garcinia hanburyi.[Pubmed:16462081]

Chem Pharm Bull (Tokyo). 2006 Feb;54(2):265-7.

Thirteen xanthones (1-13) were isolated from the resin of Garcinia hanburyi. Among them, two new compounds (namely Gaudichaudic acid, and isogambogenic acid, 1, 2), and one new natural product (deoxygaudichaudione A, 3) were identified on the basis of extensive spectral evidence including detailed 2D NMR data. Ten of these xanthones were tested for their cytotoxicities against human leukemia K562 (K562/S) and doxorubicin-resistant K562 (K562/R) cell lines, and showed similar inhibitory effects on both cell lines, suggesting that this group of polyprenylated xanthones might not be multidrug resistance (MDR) substrates.

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