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30-Hydroxygambogic acid

CAS# 881027-36-7

30-Hydroxygambogic acid

Catalog No. BCN3081----Order now to get a substantial discount!

Product Name & Size Price Stock
30-Hydroxygambogic acid: 5mg Please Inquire In Stock
30-Hydroxygambogic acid: 10mg Please Inquire In Stock
30-Hydroxygambogic acid: 20mg Please Inquire Please Inquire
30-Hydroxygambogic acid: 50mg Please Inquire Please Inquire
30-Hydroxygambogic acid: 100mg Please Inquire Please Inquire
30-Hydroxygambogic acid: 200mg Please Inquire Please Inquire
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Quality Control of 30-Hydroxygambogic acid

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Chemical structure

30-Hydroxygambogic acid

3D structure

Chemical Properties of 30-Hydroxygambogic acid

Cas No. 881027-36-7 SDF Download SDF
PubChem ID 102004804 Appearance Powder
Formula C38H44O9 M.Wt 644.8
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(=CCCC1(C=CC2=C(O1)C(=C3C(=C2O)C(=O)C4=CC5CC6C4(O3)C(C5=O)(OC6(C)C)CC=C(CO)C(=O)O)CC=C(C)C)C)C
Standard InChIKey MNNVIONVHRRQPF-CCXRYARJSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 30-Hydroxygambogic acid

The herbs of Garcinia hanburyi Hook. f.

Biological Activity of 30-Hydroxygambogic acid

Description1. 30-Hydroxygambogic acid exhibits significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines.

30-Hydroxygambogic acid Dilution Calculator

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30-Hydroxygambogic acid Molarity Calculator

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Preparing Stock Solutions of 30-Hydroxygambogic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5509 mL 7.7543 mL 15.5087 mL 31.0174 mL 38.7717 mL
5 mM 0.3102 mL 1.5509 mL 3.1017 mL 6.2035 mL 7.7543 mL
10 mM 0.1551 mL 0.7754 mL 1.5509 mL 3.1017 mL 3.8772 mL
50 mM 0.031 mL 0.1551 mL 0.3102 mL 0.6203 mL 0.7754 mL
100 mM 0.0155 mL 0.0775 mL 0.1551 mL 0.3102 mL 0.3877 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 30-Hydroxygambogic acid

A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges.[Pubmed:17193222]

Chem Biodivers. 2006 Jan;3(1):101-5.

Two new polyprenylated xanthone epimers were isolated from gamboges of Garcinia hanburyi, and identified by detailed spectroscopic analysis as 30-Hydroxygambogic acid (2a) and its (2S)-epimer 30-hydroxyepigambogic acid (2b). Both compounds exhibited significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines (Table 2).

Rapid determination of polyprenylated xanthones in gamboge resin of Garcinia hanburyi by HPLC.[Pubmed:17396587]

J Sep Sci. 2007 Feb;30(3):304-9.

A rapid ion-pair HPLC method was developed and validated for the determination of eight polyprenylated xanthones including three pairs of epimers, namely morellic acid (MA), 30-Hydroxygambogic acid (HGA), 30-hydroxyepigambogic acid (HEGA), isogambogic acid (IGA), epiisogambogic acid (EIGA), gambogenic acid (GNA), gambogic acid (GA), and epigambogic acid (EGA), in gamboge resin of Garcinia hanburyi. The separation was performed on a narrow bore C8 column with isocratic elution using a mixture of methanol-ACN-40 mM KH2PO4 buffer (37.5:37.5:25 v/v/v, containing 0.1% tetradecyltrimethylammonium bromide). The newly developed method was used to determine the contents of the eight compounds present in the gamboge. Results showed that GA and EGA are the dominant components of gamboge. The content ratio of each epimer pair remained constant, indicating that the content ratio of epimers can be used as a specific characteristic for the quality control of gamboge.

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