Desoxygambogenin

CAS# 173614-93-2

Desoxygambogenin

Catalog No. BCN3068----Order now to get a substantial discount!

Product Name & Size Price Stock
Desoxygambogenin: 5mg Please Inquire In Stock
Desoxygambogenin: 10mg Please Inquire In Stock
Desoxygambogenin: 20mg Please Inquire Please Inquire
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Desoxygambogenin: 100mg Please Inquire Please Inquire
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Desoxygambogenin: 500mg Please Inquire Please Inquire
Desoxygambogenin: 1000mg Please Inquire Please Inquire

Quality Control of Desoxygambogenin

Number of papers citing our products

Chemical structure

Desoxygambogenin

3D structure

Chemical Properties of Desoxygambogenin

Cas No. 173614-93-2 SDF Download SDF
PubChem ID 70639878 Appearance Powder
Formula C38H48O6 M.Wt 600.8
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(=CCCC(=CCC1=C(C2=C(C(=C1O)CC=C(C)C)OC34C5CC(C=C3C2=O)C(=O)C4(OC5(C)C)CC=C(C)C)O)C)C
Standard InChIKey BYSLEZZCJZXNQG-ZWUALNCXSA-N
Standard InChI InChI=1S/C38H48O6/c1-21(2)11-10-12-24(7)14-16-26-31(39)27(15-13-22(3)4)34-30(32(26)40)33(41)28-19-25-20-29-36(8,9)44-37(35(25)42,18-17-23(5)6)38(28,29)43-34/h11,13-14,17,19,25,29,39-40H,10,12,15-16,18,20H2,1-9H3/b24-14+/t25-,29?,37?,38-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Desoxygambogenin

The herbs of Garcinia hanburyi Hook. f.

Biological Activity of Desoxygambogenin

Description1. Desoxygambogenin has anti-HIV-1 activity. 2. Desoxygambogenin is a cytotoxic xanthone.
TargetsHIV

Desoxygambogenin Dilution Calculator

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Desoxygambogenin Molarity Calculator

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Preparing Stock Solutions of Desoxygambogenin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6644 mL 8.3222 mL 16.6445 mL 33.2889 mL 41.6112 mL
5 mM 0.3329 mL 1.6644 mL 3.3289 mL 6.6578 mL 8.3222 mL
10 mM 0.1664 mL 0.8322 mL 1.6644 mL 3.3289 mL 4.1611 mL
50 mM 0.0333 mL 0.1664 mL 0.3329 mL 0.6658 mL 0.8322 mL
100 mM 0.0166 mL 0.0832 mL 0.1664 mL 0.3329 mL 0.4161 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Desoxygambogenin

Cytotoxic and anti-HIV-1 caged xanthones from the resin and fruits of Garcinia hanburyi.[Pubmed:17117343]

Planta Med. 2007 Jan;73(1):33-40.

Three new caged xanthones, 7-methoxydesoxymorellin (1), 2-isoprenylforbesione (2) and 8,8a-epoxymorellic acid (3), together with nine known caged xanthones were isolated from the EtOAc extracts of resin and fruits of Garcinia hanburyi. The structures were determined by spectroscopic methods. Most of the isolated compounds showed significant cytotoxicities against a panel of mammalian cancer cell lines. Compound 3, together with the known compounds desoxymorellin, morellic acid, gambogic acid, hanburin, forbesione and dihydroisomorellin, exhibited anti-HIV-1 activity in the reverse transcriptase (RT) assay while the known compounds Desoxygambogenin and dihydroisomorellin were found moderately active in the syncytium assay. This work represents the first report on the anti-HIV-1 activities of caged xanthones.

Cytotoxic xanthones from Garcinia hanburyi.[Pubmed:8835458]

Phytochemistry. 1996 Feb;41(3):815-20.

Eleven novel cytotoxic xanthones, gambogin, morellin dimethyl acetal, isomoreollin B, moreollic acid, gambogenic acid, gambogenin, isogambogenin, Desoxygambogenin, gambogenin dimethyl acetal, gambogellic acid and hanburin were isolated together with four known xanthones, gambogic acid, isomorellin, morellic acid and desoxymorellin, from the dry latex of Garcinia hanburyi. The structures were elucidated by a detailed spectroscopic analysis.

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