Mogroside IVa

CAS# 88901-41-1

Mogroside IVa

2D Structure

Catalog No. BCN3165----Order now to get a substantial discount!

Product Name & Size Price Stock
Mogroside IVa: 5mg $219 In Stock
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Quality Control of Mogroside IVa

3D structure

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Mogroside IVa

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Chemical Properties of Mogroside IVa

Cas No. 88901-41-1 SDF Download SDF
PubChem ID 73321046 Appearance Powder
Formula C54H92O24 M.Wt 1125.3
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 2-(hydroxymethyl)-6-[[3,4,5-trihydroxy-6-[[11-hydroxy-17-[6-hydroxy-6-methyl-5-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyheptan-2-yl]-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-2-yl]methoxy]oxane-3,4,5-triol
SMILES CC(CCC(C(C)(C)O)OC1C(C(C(C(O1)COC2C(C(C(C(O2)CO)O)O)O)O)O)O)C3CCC4(C3(CC(C5(C4CC=C6C5CCC(C6(C)C)OC7C(C(C(C(O7)COC8C(C(C(C(O8)CO)O)O)O)O)O)O)C)O)C)C
Standard InChIKey OKGRRPCHOJYNKX-UHFFFAOYSA-N
Standard InChI InChI=1S/C54H92O24/c1-22(9-13-33(51(4,5)70)78-49-45(69)41(65)37(61)29(76-49)21-72-47-43(67)39(63)35(59)27(19-56)74-47)23-15-16-52(6)30-12-10-24-25(54(30,8)31(57)17-53(23,52)7)11-14-32(50(24,2)3)77-48-44(68)40(64)36(60)28(75-48)20-71-46-42(66)38(62)34(58)26(18-55)73-46/h10,22-23,25-49,55-70H,9,11-21H2,1-8H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Mogroside IVa

The fruits of Siraitia grosvenorii Swingle.

Biological Activity of Mogroside IVa

DescriptionMogroside IVa is a natural product from Siraitia grosvenorii Swingle.

Protocol of Mogroside IVa

Structure Identification
Nat Prod Commun. 2009 Jun;4(6):769-72.

A minor, sweet cucurbitane glycoside from Siraitia grosvenorii.[Pubmed: 19634319]

A minor, sweet cucurbitane-glycoside, named iso-mogroside V (1), was isolated from Luo Han Guo (Siraitia grosvenorii (Swingle) C. Jeffery) along with five previously reported mogrosides.
METHODS AND RESULTS:
The structure of iso-mogroside V, 3-[(4-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-mogrol-24-O-beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->6)]beta-D-glucopyranoside, was established on the basis of extensive 2D-NMR (COSY, TOCSY, NOESY, HSQC, and HMBC) and LCMS analyses.
CONCLUSIONS:
The five known mogrosides were identified as mogroside V (2), 11-oxo-mogroside V (3), siamenoside I (4), Mogroside IVa (5) and Mogroside IVe (6). Iso-mogroside V was determined to be approximately 500 times sweeter than 0.5% (w/v) sucrose.

Mogroside IVa Dilution Calculator

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Mogroside IVa Molarity Calculator

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Preparing Stock Solutions of Mogroside IVa

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.8887 mL 4.4433 mL 8.8865 mL 17.773 mL 22.2163 mL
5 mM 0.1777 mL 0.8887 mL 1.7773 mL 3.5546 mL 4.4433 mL
10 mM 0.0889 mL 0.4443 mL 0.8887 mL 1.7773 mL 2.2216 mL
50 mM 0.0178 mL 0.0889 mL 0.1777 mL 0.3555 mL 0.4443 mL
100 mM 0.0089 mL 0.0444 mL 0.0889 mL 0.1777 mL 0.2222 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Mogroside IVa

A minor, sweet cucurbitane glycoside from Siraitia grosvenorii.[Pubmed:19634319]

Nat Prod Commun. 2009 Jun;4(6):769-72.

A minor, sweet cucurbitane-glycoside, named iso-mogroside V (1), was isolated from Luo Han Guo (Siraitia grosvenorii (Swingle) C. Jeffery) along with five previously reported mogrosides. The structure of iso-mogroside V, 3-[(4-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-mogrol-24-O-beta-D-gluco pyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->6)]beta-D-glucopyranoside, was established on the basis of extensive 2D-NMR (COSY, TOCSY, NOESY, HSQC, and HMBC) and LCMS analyses. The five known mogrosides were identified as mogroside V (2), 11-oxo-mogroside V (3), siamenoside I (4), mogrosides IVa (5) and IVe (6). Iso-mogroside V was determined to be approximately 500 times sweeter than 0.5% (w/v) sucrose.

Description

Mogroside IV-A, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.

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