Iso-mogroside V

CAS# 1126032-65-2

Iso-mogroside V

2D Structure

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Iso-mogroside V: 5mg $345 In Stock
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Quality Control of Iso-mogroside V

3D structure

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Iso-mogroside V

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Chemical Properties of Iso-mogroside V

Cas No. 1126032-65-2 SDF Download SDF
PubChem ID 102004811 Appearance White powder
Formula C60H102O29 M.Wt 1287.5
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in DMSO and methan
Chemical Name (2R,3R,4S,5S,6R)-2-[[(2R,3S,4S,5R,6S)-6-[(3R,6R)-6-[(3S,8R,9R,10R,11R,13R,14S,17R)-3-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-11-hydroxy-4,4,9,13,14-pentamethyl-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-hydroxy-2-methylheptan-3-yl]oxy-3,4-dihydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES CC(CCC(C(C)(C)O)OC1C(C(C(C(O1)COC2C(C(C(C(O2)CO)O)O)O)O)O)OC3C(C(C(C(O3)CO)O)O)O)C4CCC5(C4(CC(C6(C5CC=C7C6CCC(C7(C)C)OC8C(C(C(C(O8)CO)OC9C(C(C(C(O9)CO)O)O)O)O)O)C)O)C)C
Standard InChIKey SQKPHECGTGXVQW-SYUMKSFFSA-N
Standard InChI InChI=1S/C60H102O29/c1-23(9-13-35(57(4,5)79)87-55-50(89-54-47(77)42(72)38(68)29(20-63)83-54)43(73)39(69)31(85-55)22-80-51-45(75)40(70)36(66)27(18-61)81-51)24-15-16-58(6)32-12-10-25-26(60(32,8)33(65)17-59(24,58)7)11-14-34(56(25,2)3)86-52-48(78)44(74)49(30(21-64)84-52)88-53-46(76)41(71)37(67)28(19-62)82-53/h10,23-24,26-55,61-79H,9,11-22H2,1-8H3/t23-,24-,26-,27-,28-,29-,30-,31-,32-,33-,34+,35-,36-,37-,38-,39-,40+,41+,42+,43+,44-,45-,46-,47-,48-,49-,50-,51-,52+,53+,54+,55+,58+,59-,60+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Iso-mogroside V

The fruits of Siraitia grosvenorii Swingle.

Biological Activity of Iso-mogroside V

DescriptionIso-mogroside V is approximately 500 times sweeter than 0.5% (w/v) sucrose.

Protocol of Iso-mogroside V

Structure Identification
Nat Prod Commun. 2009 Jun;4(6):769-72.

A minor, sweet cucurbitane glycoside from Siraitia grosvenorii.[Pubmed: 19634319]


METHODS AND RESULTS:
A minor, sweet cucurbitane-glycoside, named Iso-mogroside V (1), was isolated from Luo Han Guo (Siraitia grosvenorii (Swingle) C. Jeffery) along with five previously reported mogrosides. The structure of Iso-mogroside V, 3-[(4-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-mogrol-24-O-beta-D-glucopyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->6)]beta-D-glucopyranoside, was established on the basis of extensive 2D-NMR (COSY, TOCSY, NOESY, HSQC, and HMBC) and LCMS analyses.
CONCLUSIONS:
The five known mogrosides were identified as mogroside V (2), 11-oxo-mogroside V (3), siamenoside I (4), mogrosides IVa (5) and IVe (6). Iso-mogroside V was determined to be approximately 500 times sweeter than 0.5% (w/v) sucrose.

Iso-mogroside V Dilution Calculator

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Iso-mogroside V Molarity Calculator

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Preparing Stock Solutions of Iso-mogroside V

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.7767 mL 3.8835 mL 7.767 mL 15.534 mL 19.4175 mL
5 mM 0.1553 mL 0.7767 mL 1.5534 mL 3.1068 mL 3.8835 mL
10 mM 0.0777 mL 0.3883 mL 0.7767 mL 1.5534 mL 1.9417 mL
50 mM 0.0155 mL 0.0777 mL 0.1553 mL 0.3107 mL 0.3883 mL
100 mM 0.0078 mL 0.0388 mL 0.0777 mL 0.1553 mL 0.1942 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Iso-mogroside V

A minor, sweet cucurbitane glycoside from Siraitia grosvenorii.[Pubmed:19634319]

Nat Prod Commun. 2009 Jun;4(6):769-72.

A minor, sweet cucurbitane-glycoside, named Iso-mogroside V (1), was isolated from Luo Han Guo (Siraitia grosvenorii (Swingle) C. Jeffery) along with five previously reported mogrosides. The structure of Iso-mogroside V, 3-[(4-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-mogrol-24-O-beta-D-gluco pyranosyl-(1-->2)-O-[beta-D-glucopyranosyl-(1-->6)]beta-D-glucopyranoside, was established on the basis of extensive 2D-NMR (COSY, TOCSY, NOESY, HSQC, and HMBC) and LCMS analyses. The five known mogrosides were identified as mogroside V (2), 11-oxo-mogroside V (3), siamenoside I (4), mogrosides IVa (5) and IVe (6). Iso-mogroside V was determined to be approximately 500 times sweeter than 0.5% (w/v) sucrose.

Description

Isomogroside V is a sweetener, which extracted from Siraitia grosvenorii (Swingle).

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