3,6-Dihydroxy-1,2,7-trimethoxyxanthoneCAS# 916210-79-2 |
Quality Control & MSDS
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| Cas No. | 916210-79-2 | SDF | Download SDF |
| PubChem ID | 56928514 | Appearance | Powder |
| Formula | C16H14O7 | M.Wt | 318.28 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3,6-dihydroxy-1,2,7-trimethoxyxanthen-9-one | ||
| SMILES | COC1=C(C=C2C(=C1)C(=O)C3=C(O2)C=C(C(=C3OC)OC)O)O | ||
| Standard InChIKey | CAFZLSJOANEDGR-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C16H14O7/c1-20-11-4-7-10(5-8(11)17)23-12-6-9(18)15(21-2)16(22-3)13(12)14(7)19/h4-6,17-18H,1-3H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
3,6-Dihydroxy-1,2,7-trimethoxyxanthone Dilution Calculator
3,6-Dihydroxy-1,2,7-trimethoxyxanthone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1419 mL | 15.7094 mL | 31.4189 mL | 62.8378 mL | 78.5472 mL |
| 5 mM | 0.6284 mL | 3.1419 mL | 6.2838 mL | 12.5676 mL | 15.7094 mL |
| 10 mM | 0.3142 mL | 1.5709 mL | 3.1419 mL | 6.2838 mL | 7.8547 mL |
| 50 mM | 0.0628 mL | 0.3142 mL | 0.6284 mL | 1.2568 mL | 1.5709 mL |
| 100 mM | 0.0314 mL | 0.1571 mL | 0.3142 mL | 0.6284 mL | 0.7855 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Chemical constituents of Polygala tenuifolia roots and their inhibitory activity on lipopolysaccharide-induced nitric oxide production in BV2 microglia.[Pubmed:21740104]
J Enzyme Inhib Med Chem. 2012 Feb;27(1):1-4.
A methanolic extract of the roots of Polygala tenuifolia (Polygalaceae) significantly attenuated nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated BV2 microglia cells. Five xanthones, 1-hydroxy-7-methoxyxanthone (1), 3,6-Dihydroxy-1,2,7-trimethoxyxanthone (2), 1,3,6-trihydroxy-2,7-dimethoxyxanthone (3), 1,7-dihydroxy-2,3-dimethoxyxanthone (4) and 1,7-dihydroxy-3-methoxyxanthone (5), and five phenylpropanoids, 4-hydroxy-3-methoxypropiophenone (6), methyl 4-hydroxy-3-methoxycinnamic acid (7), 3,4,5-trimethoxycinnamic acid (8), 4-methoxycinnamic acid (9) and beta-d-(3-O-sinapoyl) fructofuranosyl-alpha-d-(6-O-sinapoyl)glucopyranoside (10), were isolated from CHCl(3) fraction using bioactivity-guided fractionation. Among these compounds, compounds 1, 2, 4, 5 and 7 showed significant inhibitory effects on LPS-induced NO production in BV2 microglia cells at the concentration ranging from 10.0 to 100.0 muM.
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