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3-O-p-Coumaroyloleanolic acid

CAS# 151334-06-4

3-O-p-Coumaroyloleanolic acid

2D Structure

Catalog No. BCN3952----Order now to get a substantial discount!

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Quality Control of 3-O-p-Coumaroyloleanolic acid

3D structure

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3-O-p-Coumaroyloleanolic acid

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Chemical Properties of 3-O-p-Coumaroyloleanolic acid

Cas No. 151334-06-4 SDF Download SDF
PubChem ID 10579517 Appearance Powder
Formula C39H54O5 M.Wt 602.9
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
SMILES CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)OC(=O)C=CC6=CC=C(C=C6)O)C)C)C2C1)C)C(=O)O)C
Standard InChIKey PSKOYUFGDWKJBO-CEDKKCENSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 3-O-p-Coumaroyloleanolic acid

The roots of Sanguisorba officinalis

Biological Activity of 3-O-p-Coumaroyloleanolic acid

In vitro

Triterpenoids from Hippophae rhamnoides L. and Their Nitric Oxide Production-Inhibitory and DPPH Radical-Scavenging Activities.[Reference: WebLink]

CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55(1):15-18.


METHODS AND RESULTS:
In our investigation on the chemical constituents of Hippophae rhamnoides L., the chloroform-soluble fraction of the 80% acetone extract of branch bark was observed to inhibit nitric oxide (NO) production in a lipopolysaccharide and recombinant mouse interferon-gamma-activated murine macrophage-like cell line, RAW 264.7 cells. Two new triterpenoids, 2-O-trans-p-coumaroyl maslinic acid (1) and 2-O-caffeoyl maslinic acid (2), and three known triterpenoids, oleanolic acid (3), 3-O-trans-p-coumaroyl oleanolic acid (3-O-p-Coumaroyloleanolic acid, 4), and 3-O-caffeoyl oleanolic acid (5), and 6-methoxy-2H-1-benzopyran (6) and beta-sitosterol (7) were isolated from the branch bark extract.
CONCLUSIONS:
Their inhibitory activities on the production of NO in RAW 264.7 cells and radical-scavenging activities were examined.

3-O-p-Coumaroyloleanolic acid Dilution Calculator

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3-O-p-Coumaroyloleanolic acid Molarity Calculator

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Preparing Stock Solutions of 3-O-p-Coumaroyloleanolic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6586 mL 8.2932 mL 16.5865 mL 33.173 mL 41.4662 mL
5 mM 0.3317 mL 1.6586 mL 3.3173 mL 6.6346 mL 8.2932 mL
10 mM 0.1659 mL 0.8293 mL 1.6586 mL 3.3173 mL 4.1466 mL
50 mM 0.0332 mL 0.1659 mL 0.3317 mL 0.6635 mL 0.8293 mL
100 mM 0.0166 mL 0.0829 mL 0.1659 mL 0.3317 mL 0.4147 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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