Pseudolarolide B

CAS# 151368-43-3

Pseudolarolide B

Catalog No. BCN8093----Order now to get a substantial discount!

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Quality Control of Pseudolarolide B

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Chemical structure

Pseudolarolide B

3D structure

Chemical Properties of Pseudolarolide B

Cas No. 151368-43-3 SDF Download SDF
PubChem ID 21592337 Appearance Powder
Formula C30H42O4 M.Wt 466.65
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,4R,5R,6R,8S,10R,12S,13S,16R,21R)-3',4,6,12,17,17-hexamethylspiro[9-oxahexacyclo[11.9.0.01,21.04,12.05,10.016,21]docosane-8,5'-furan]-2',18-dione
SMILES CC1CC2(C=C(C(=O)O2)C)OC3C1C4(CCC56CC57CCC(=O)C(C7CCC6C4(C3)C)(C)C)C
Standard InChIKey ULWBDUNMGKITLY-JCWARNQUSA-N
Standard InChI InChI=1S/C30H42O4/c1-17-13-30(14-18(2)24(32)34-30)33-19-15-27(6)21-8-7-20-25(3,4)22(31)9-10-28(20)16-29(21,28)12-11-26(27,5)23(17)19/h14,17,19-21,23H,7-13,15-16H2,1-6H3/t17-,19-,20+,21+,23+,26-,27+,28-,29+,30+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pseudolarolide B

The peel of Pseudolarix amabilis

Biological Activity of Pseudolarolide B

In vitro

Antimicrobial, cytotoxic lignans and terpenoids from the twigs of Pseudolarix kaempferi.[Pubmed: 21728150]

Planta Med. 2011 Nov;77(17):1924-31.


METHODS AND RESULTS:
Seven new compounds, including four lignans, (+)-(8S,8′S)-9,9′-dibenzoylsecoisolariciresinol (1), (+)-(8S*,8′R*)-4,4′-dimethyloxomatairesinol (2), (+)-(7S*,8R*,8′R*,9′S*)-9′-n-butoxytsugacetal (3), and pseudolarkaemin A (4), a pyronane glycoside, pseudolarkaemin B (5), an ent-beyerene glycoside, pseudolarkaemin C (6), and a triterpene, 25-epi-pseudolarolide Q (7), along with 25 known compounds (8–32) were isolated from the twigs of Pseudolarix kaempferi. Their structures were elucidated mainly by the analysis of their NMR and MS data. Pseudolarolide C acid (24) was isolated for the first time as a natural product. All compounds were evaluated for antimicrobial activity against Candida albicans and Staphylococcus aureus, and cytotoxic activity against K562, HT-29, B16, BGC-823, BEL-7402, SGC-7901, U251, and A549 cancer cell lines were assayed.
CONCLUSIONS:
Results indicated that the new compounds 3, 7, and some known compounds showed antimicrobial and cytotoxic activities.

Pseudolarolide B Dilution Calculator

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Pseudolarolide B Molarity Calculator

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Preparing Stock Solutions of Pseudolarolide B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1429 mL 10.7147 mL 21.4293 mL 42.8587 mL 53.5733 mL
5 mM 0.4286 mL 2.1429 mL 4.2859 mL 8.5717 mL 10.7147 mL
10 mM 0.2143 mL 1.0715 mL 2.1429 mL 4.2859 mL 5.3573 mL
50 mM 0.0429 mL 0.2143 mL 0.4286 mL 0.8572 mL 1.0715 mL
100 mM 0.0214 mL 0.1071 mL 0.2143 mL 0.4286 mL 0.5357 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pseudolarolide B

Antimicrobial, cytotoxic lignans and terpenoids from the twigs of Pseudolarix kaempferi.[Pubmed:21728150]

Planta Med. 2011 Nov;77(17):1924-31.

Seven new compounds, including four lignans, (+)-(8S,8'S)-9,9'-dibenzoylsecoisolariciresinol (1), (+)-(8S*,8'R*)-4,4'-dimethyloxomatairesinol (2), (+)-(7S*,8R*,8'R*,9'S*)-9'-n-butoxytsugacetal (3), and pseudolarkaemin A (4), a pyronane glycoside, pseudolarkaemin B (5), an ent-beyerene glycoside, pseudolarkaemin C (6), and a triterpene, 25-epi-pseudolarolide Q (7), along with 25 known compounds (8-32) were isolated from the twigs of Pseudolarix kaempferi. Their structures were elucidated mainly by the analysis of their NMR and MS data. Pseudolarolide C acid (24) was isolated for the first time as a natural product. All compounds were evaluated for antimicrobial activity against Candida albicans and Staphylococcus aureus, and cytotoxic activity against K562, HT-29, B16, BGC-823, BEL-7402, SGC-7901, U251, and A549 cancer cell lines were assayed. Results indicated that the new compounds 3, 7, and some known compounds showed antimicrobial and cytotoxic activities.

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