5-Deoxystrigol

CAS# 151716-18-6

5-Deoxystrigol

2D Structure

Catalog No. BCN7693----Order now to get a substantial discount!

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5-Deoxystrigol: 5mg $960 In Stock
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Quality Control of 5-Deoxystrigol

3D structure

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5-Deoxystrigol

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Chemical Properties of 5-Deoxystrigol

Cas No. 151716-18-6 SDF Download SDF
PubChem ID 15102684 Appearance Powder
Formula C19H22O5 M.Wt 330.37
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3E,3aR,8bS)-8,8-dimethyl-3-[[(2R)-4-methyl-5-oxo-2H-furan-2-yl]oxymethylidene]-3a,4,5,6,7,8b-hexahydroindeno[1,2-b]furan-2-one
SMILES CC1=CC(OC1=O)OC=C2C3CC4=C(C3OC2=O)C(CCC4)(C)C
Standard InChIKey QXTUQXRFEBHUBA-DYLOANJQSA-N
Standard InChI InChI=1S/C19H22O5/c1-10-7-14(23-17(10)20)22-9-13-12-8-11-5-4-6-19(2,3)15(11)16(12)24-18(13)21/h7,9,12,14,16H,4-6,8H2,1-3H3/b13-9+/t12-,14-,16+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 5-Deoxystrigol

The root exudate of Striga hermonthica (Del.) Benth.

Biological Activity of 5-Deoxystrigol

Description1. 5-Deoxystrigol is a highly active Striga germination stimulant. 2. 5-Deoxystrigol has a protective effect on D-galactosamine (D-GalN) induced mice acute liver injury and has a protective effect on CCl4 induced mice acute liver injury.

5-Deoxystrigol Dilution Calculator

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5-Deoxystrigol Molarity Calculator

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Preparing Stock Solutions of 5-Deoxystrigol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0269 mL 15.1345 mL 30.2691 mL 60.5382 mL 75.6727 mL
5 mM 0.6054 mL 3.0269 mL 6.0538 mL 12.1076 mL 15.1345 mL
10 mM 0.3027 mL 1.5135 mL 3.0269 mL 6.0538 mL 7.5673 mL
50 mM 0.0605 mL 0.3027 mL 0.6054 mL 1.2108 mL 1.5135 mL
100 mM 0.0303 mL 0.1513 mL 0.3027 mL 0.6054 mL 0.7567 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 5-Deoxystrigol

Mutation in sorghum LOW GERMINATION STIMULANT 1 alters strigolactones and causes Striga resistance.[Pubmed:28396420]

Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):4471-4476.

Striga is a major biotic constraint to sorghum production in semiarid tropical Africa and Asia. Genetic resistance to this parasitic weed is the most economically feasible control measure. Mutant alleles at the LGS1 (LOW GERMINATION STIMULANT 1) locus drastically reduce Striga germination stimulant activity. We provide evidence that the responsible gene at LGS1 codes for an enzyme annotated as a sulfotransferase and show that functional loss of this gene results in a change of the dominant strigolactone (SL) in root exudates from 5-Deoxystrigol, a highly active Striga germination stimulant, to orobanchol, an SL with opposite stereochemistry. Orobanchol, although not previously reported in sorghum, functions in the multiple SL roles required for normal growth and environmental responsiveness but does not stimulate germination of Striga This work describes the identification of a gene regulating Striga resistance and the underlying protective chemistry resulting from mutation.

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