5'-S-Methyl-5'-thioadenosineCAS# 2457-80-9 |
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| Cas No. | 2457-80-9 | SDF | Download SDF |
| PubChem ID | 149 | Appearance | Powder |
| Formula | C11H15N5O3S | M.Wt | 297.3 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | DMSO : 50 mg/mL (168.16 mM; Need ultrasonic) DMF : 2.5 mg/mL (8.41 mM; Need ultrasonic) H2O : 1 mg/mL (3.36 mM; Need ultrasonic) | ||
| Chemical Name | 2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol | ||
| SMILES | CSCC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O | ||
| Standard InChIKey | WUUGFSXJNOTRMR-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herb of Ephedra distachya
| Description | 1. S-Methyl-5′-thioadenosine can inhibit the activity of ThiC (4-amino-5-hydroxymethyl-2- methylpyrimidine phosphate synthase). |
| Targets | Adenosine Receptor |
5'-S-Methyl-5'-thioadenosine Dilution Calculator
5'-S-Methyl-5'-thioadenosine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.3636 mL | 16.818 mL | 33.6361 mL | 67.2721 mL | 84.0901 mL |
| 5 mM | 0.6727 mL | 3.3636 mL | 6.7272 mL | 13.4544 mL | 16.818 mL |
| 10 mM | 0.3364 mL | 1.6818 mL | 3.3636 mL | 6.7272 mL | 8.409 mL |
| 50 mM | 0.0673 mL | 0.3364 mL | 0.6727 mL | 1.3454 mL | 1.6818 mL |
| 100 mM | 0.0336 mL | 0.1682 mL | 0.3364 mL | 0.6727 mL | 0.8409 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Isolation and structure elucidation of chemical constituents from Pinellia ternata].[Pubmed:24761673]
Zhong Yao Cai. 2013 Oct;36(10):1620-2.
OBJECTIVE: To isolate and identify the chemical constituents of ethanol extract of Pinellia ternata. METHODS: The constituents were isolated by silica-gel, Sephadex LH-20 chromatography and HPLC techniques. The structures were identified by spectroscopic analysis including 2D NMR techniques and chemical properties. RESULTS: Nine compounds were obtained and identified as uridine (1), 5'-S-methyl-5'-thioadenosine (2), adenine (3), chrysophanol (4), 5-hydroxymethylfurfural (5), nicotinamide (6), (2S)-1-O-(9Z, 12Z-octadecadienoyl)-3-O-beta-galactopyranosylglycerol (7), daucosterol (8), beta-sitosterol (9). CONCLUSION: Compounds 2, 6, 7 are isolated from this plant for the first time.
5'-Methylthioadenosine is produced from S-adenosylmethionine and behaves as a powful inhibitory product.
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