AbrineCAS# 526-31-8 |
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Number of papers citing our products
| Cas No. | 526-31-8 | SDF | Download SDF |
| PubChem ID | 160511 | Appearance | Cryst. |
| Formula | C12H14N2O2 | M.Wt | 218.25 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | H2O : 2 mg/mL (9.16 mM; ultrasonic and adjust pH to 10 with NaOH) | ||
| Chemical Name | (2S)-3-(1H-indol-3-yl)-2-methylaminopropanoic acid | ||
| SMILES | CNC(CC1=CNC2=CC=CC=C21)C(=O)O | ||
| Standard InChIKey | CZCIKBSVHDNIDH-NSHDSACASA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Abrine shows comparable ABTS radical cation scavenging activities and reduces power to two commercial antioxidants (BHT and Trolox). |
| In vitro | In vitro antioxidant activities and anti-proliferative properties of the functional herb Abrus cantoniensis and its main alkaloid abrine.[Pubmed: 25059572 ]Food Funct. 2014 Sep;5(9):2268-77.Abrus cantoniensis is a common and popular vegetative food consumed as beverage, soup and folk medicine in the tropical and subtropical areas of Asia. It has been claimed valuable for cleansing toxicants in the liver. However, the functional effects of A. cantoniensis have not yet been scientifically explored. This study comprehensively evaluated the in vitro antioxidant and anti-proliferative capacities of the herbal extract and the main alkaloid Abrine. |
Abrine Dilution Calculator
Abrine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.5819 mL | 22.9095 mL | 45.819 mL | 91.638 mL | 114.5475 mL |
| 5 mM | 0.9164 mL | 4.5819 mL | 9.1638 mL | 18.3276 mL | 22.9095 mL |
| 10 mM | 0.4582 mL | 2.291 mL | 4.5819 mL | 9.1638 mL | 11.4548 mL |
| 50 mM | 0.0916 mL | 0.4582 mL | 0.9164 mL | 1.8328 mL | 2.291 mL |
| 100 mM | 0.0458 mL | 0.2291 mL | 0.4582 mL | 0.9164 mL | 1.1455 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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In vitro antioxidant activities and anti-proliferative properties of the functional herb Abrus cantoniensis and its main alkaloid abrine.[Pubmed:25059572]
Food Funct. 2014 Sep;5(9):2268-77.
Abrus cantoniensis is a common and popular vegetative food consumed as beverage, soup and folk medicine in the tropical and subtropical areas of Asia. It has been claimed valuable for cleansing toxicants in the liver. However, the functional effects of A. cantoniensis have not yet been scientifically explored. This study comprehensively evaluated the in vitro antioxidant and anti-proliferative capacities of the herbal extract and the main alkaloid Abrine. Abrine was qualitatively and quantitatively determined in methanol extract (ME) using HPLC-DAD and LC-MS/MS. The results showed that ME, ethyl acetate fraction (EF) and Abrine exhibited comparable ABTS radical cation scavenging activities and reducing power to two commercial antioxidants (BHT and Trolox). The EF exerted strong cellular antioxidant activity and selective cytotoxicity against three cancer cell lines in a dose-dependent manner. Biological assays revealed that the EF induced cell cycle arrest at G2/M and apoptosis in MCF-7 and Hep3B cells after 48 h of treatment. Thus, A. cantoniensis exerted potent cellular antioxidant and anti-proliferative properties, highlighting why it has been traditionally used as a functional food.
