Iriflophenone

CAS# 52591-10-3

Iriflophenone

Catalog No. BCN5679----Order now to get a substantial discount!

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Iriflophenone: 5mg $725 In Stock
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Quality Control of Iriflophenone

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Chemical structure

Iriflophenone

3D structure

Chemical Properties of Iriflophenone

Cas No. 52591-10-3 SDF Download SDF
PubChem ID 11311158 Appearance Yellow powder
Formula C13H10O5 M.Wt 246.2
Type of Compound Xanthones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4-hydroxyphenyl)-(2,4,6-trihydroxyphenyl)methanone
SMILES C1=CC(=CC=C1C(=O)C2=C(C=C(C=C2O)O)O)O
Standard InChIKey AOJWDTJDEGSHOA-UHFFFAOYSA-N
Standard InChI InChI=1S/C13H10O5/c14-8-3-1-7(2-4-8)13(18)12-10(16)5-9(15)6-11(12)17/h1-6,14-17H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Iriflophenone

The herbs of Aquilaria sinensis

Biological Activity of Iriflophenone

TargetsEstrogen receptor | Progestogen receptor

Iriflophenone Dilution Calculator

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Iriflophenone Molarity Calculator

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Preparing Stock Solutions of Iriflophenone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0617 mL 20.3087 mL 40.6174 mL 81.2348 mL 101.5435 mL
5 mM 0.8123 mL 4.0617 mL 8.1235 mL 16.247 mL 20.3087 mL
10 mM 0.4062 mL 2.0309 mL 4.0617 mL 8.1235 mL 10.1543 mL
50 mM 0.0812 mL 0.4062 mL 0.8123 mL 1.6247 mL 2.0309 mL
100 mM 0.0406 mL 0.2031 mL 0.4062 mL 0.8123 mL 1.0154 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Iriflophenone

Effects of iriflophenone 3-C-beta-glucoside on fasting blood glucose level and glucose uptake.[Pubmed:25709215]

Pharmacogn Mag. 2015 Jan-Mar;11(41):82-9.

BACKGROUND: One of the biological activities of agar wood (Aquilaria sinensis Lour., Thymelaeaceae), is anti-hyperglycemic activity. The methanolic extract (ME) was proven to possess the fasting blood glucose activity in rat and glucose uptake transportation by rat adipocytes. OBJECTIVE: To determine the decreasing fasting blood glucose level of constituents affordable for in vivo test. If the test was positive, the mechanism which is positive to the ME, glucose transportation, will be performed. MATERIALS AND METHODS: The ME was separated by column chromatography and identified by spectroscopic methods. Mice was used as an animal model (in vivo), and rat adipocytes were used for the glucose transportation activity (in vitro). RESULT: Iriflophenone 3-C-beta-glucoside (IPG) was the main constituent, 3.17%, and tested for the activities. Insulin and the ME were used as positive controls. The ME, IPG and insulin lowered blood glucose levels by 40.3, 46.4 and 41.5%, respectively, and enhanced glucose uptake by 152, 153, and 183%, respectively. CONCLUSION: These findings suggest that IPG is active in lowering fasting blood glucose with potency comparable to that of insulin.

Assessment of extraction parameters on antioxidant capacity, polyphenol content, epigallocatechin gallate (EGCG), epicatechin gallate (ECG) and iriflophenone 3-C-beta-glucoside of agarwood (Aquilaria crassna) young leaves.[Pubmed:25153858]

Molecules. 2014 Aug 14;19(8):12304-19.

The effects of ethanol concentration (0%-100%, v/v), solid-to-solvent ratio (1:10-1:60, w/v) and extraction time (30-180 min) on the extraction of polyphenols from agarwood (Aquilaria crassna) were examined. Total phenolic content (TPC), total flavonoid content (TFC) and total flavanol (TF) assays and HPLC-DAD were used for the determination and quantification of polyphenols, flavanol gallates (epigallocatechin gallate--EGCG and epicatechin gallate--ECG) and a benzophenone (Iriflophenone 3-C-beta-glucoside) from the crude polyphenol extract (CPE) of A. crassna. 2,2'-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was used to evaluate the antioxidant capacity of the CPE. Experimental results concluded that ethanol concentration and solid-to-solvent ratio had significant effects (p<0.05) on the yields of polyphenol and antioxidant capacity. Extraction time had an insignificant influence on the recovery of EGCG, ECG and Iriflophenone 3-C-beta-glucoside, as well as radical scavenging capacity from the CPE. The extraction parameters that exhibited maximum yields were 40% (v/v) ethanol, 1:60 (w/v) for 30 min where the TPC, TFC, TF, DPPH, EGCG, ECG and Iriflophenone 3-C-beta-glucoside levels achieved were 183.5 mg GAE/g DW, 249.0 mg QE/g DW, 4.9 mg CE/g DW, 93.7%, 29.1 mg EGCG/g DW, 44.3 mg ECG/g DW and 39.9 mg Iriflophenone 3-C-beta-glucoside/g DW respectively. The IC50 of the CPE was 24.6 mg/L.

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