Ingenol 3-palmitateCAS# 52557-26-3 |
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| Cas No. | 52557-26-3 | SDF | Download SDF |
| PubChem ID | 56841025 | Appearance | Oil |
| Formula | C36H58O6 | M.Wt | 586.84 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(1S,4S,5S,6R,9S,10R,12R,14R)-5,6-dihydroxy-7-(hydroxymethyl)-3,11,11,14-tetramethyl-15-oxo-4-tetracyclo[7.5.1.01,5.010,12]pentadeca-2,7-dienyl] hexadecanoate | ||
| SMILES | CCCCCCCCCCCCCCCC(=O)OC1C(=CC23C1(C(C(=CC(C2=O)C4C(C4(C)C)CC3C)CO)O)O)C | ||
| Standard InChIKey | DOSPRDHNGNPKKJ-BYPUAWAASA-N | ||
| Standard InChI | InChI=1S/C36H58O6/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-29(38)42-33-24(2)22-35-25(3)20-28-30(34(28,4)5)27(32(35)40)21-26(23-37)31(39)36(33,35)41/h21-22,25,27-28,30-31,33,37,39,41H,6-20,23H2,1-5H3/t25-,27+,28-,30+,31-,33+,35+,36+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The latex of Euphorbia serrata.
| Description | 1. Ingenol-3-palmitate shows irritant and cocarcinogenic activity on mouse ear and on mice back skin. |
Ingenol 3-palmitate Dilution Calculator
Ingenol 3-palmitate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.704 mL | 8.5202 mL | 17.0404 mL | 34.0808 mL | 42.601 mL |
| 5 mM | 0.3408 mL | 1.704 mL | 3.4081 mL | 6.8162 mL | 8.5202 mL |
| 10 mM | 0.1704 mL | 0.852 mL | 1.704 mL | 3.4081 mL | 4.2601 mL |
| 50 mM | 0.0341 mL | 0.1704 mL | 0.3408 mL | 0.6816 mL | 0.852 mL |
| 100 mM | 0.017 mL | 0.0852 mL | 0.1704 mL | 0.3408 mL | 0.426 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Tumor promoting constituent of Euphorbia serrata L. latex.[Pubmed:971764]
Experientia. 1976 Sep 15;32(9):1196-7.
Euphorbia serrata latex has initially ingenol-3-palmitate, which by action of silica gel is converted to ingenol-20-palmitate. The former is responsible for the irritant and cocarcinogenic activity of the latex on mouse ear and on mice back skin.
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