Home >> Research Area >>Natural Products>>Diterpenoids>> 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

CAS# 158850-76-1

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Catalog No. BCN1550----Order now to get a substantial discount!

Product Name & Size Price Stock
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 5mg Please Inquire In Stock
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 10mg Please Inquire In Stock
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 20mg Please Inquire Please Inquire
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 50mg Please Inquire Please Inquire
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 100mg Please Inquire Please Inquire
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 200mg Please Inquire Please Inquire
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 500mg Please Inquire Please Inquire
3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Number of papers citing our products

Chemical structure

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

3D structure

Chemical Properties of 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Cas No. 158850-76-1 SDF Download SDF
PubChem ID 102004599 Appearance Powder
Formula C32H44O7 M.Wt 540.7
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCCCCC=CC=CC(=O)OC1C(=CC23C1(C(C(=CC(C2=O)C4C(C4(C)C)CC3C)COC(=O)C)O)O)C
Standard InChIKey SYXKKJDQNXPUSI-VNTMLSECSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

The roots of Euphorbia kansui T. N. Liou ex S. B. Ho

Biological Activity of 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Description1. 3-O-(2′E,4′Z-decadienoyl)-20-O-acetylingenol, one toxic terpenoid from raw Gansui. 2. 3-O-(2′E,4′Z-decadienoyl)-20-O-acetylingenol has strong cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships . 3. 20-O-acetyl-[3-O-(2'E,4'Z)-decadienoyl]-ingenol and 3-O-(2'E,4'Z)-decadienoylingenol show the same antinematodal activity against the nematode, Bursaphelenchus xylophilus, at a minimum effective dose (MED) of 5 microg/cotton ball. 4. 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol induces the cytotoxicity of intestinal epithelial cells of rats (IEC-6 cells) depends on induction of cell apoptosis via mitochondrial pathway and cell cycle arrest. 5. 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol, kansuinine B and kansuinine A can markedly promote SPL proliferation and NO production by PMphi at concentrations from 0.78 to 12.50 microg/mL, hence the they are believed to be important proinflammatory components of the roots of E. kansui.
TargetsNO | Antifection

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8495 mL 9.2473 mL 18.4945 mL 36.9891 mL 46.2364 mL
5 mM 0.3699 mL 1.8495 mL 3.6989 mL 7.3978 mL 9.2473 mL
10 mM 0.1849 mL 0.9247 mL 1.8495 mL 3.6989 mL 4.6236 mL
50 mM 0.037 mL 0.1849 mL 0.3699 mL 0.7398 mL 0.9247 mL
100 mM 0.0185 mL 0.0925 mL 0.1849 mL 0.3699 mL 0.4624 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Ultra-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry analysis of the impact of processing on toxic components of Kansui Radix

BMC Complem. Altern. M., 2016, 16(1):1-8.

Results showed that processing with vinegar caused conspicuous chemical changes. Among the altered components, 11 toxic terpenoids, 3-O-benzoyl-13-O- dodecanoylingenol/20-O-benzoyl-13-O-dodecanoylingenol, kansuinine D, kansuinine A, 3-O-benzoyl-13-O-dodecanoylingenol/20-O-benzoyl-13-O-dodecanoylingenol, 3-O- benzoylingenol/20-O-benzoylingenol, 20-O-(2′E,4′Z-decadienoyl)ingenol/20-O-(2′E,4′E- decadienoyl)ingenol/3-O-(2′E,4′Z-decadienoyl)ingenol/3-O-(2′E,4′E-decadienoyl)ingenol, 3-O-(2′E,4′Z-decadienoyl)-20-deoxyingenol,3-O-(2′E,4′Z-,ecadienoyl)-5-O-acetylingenol,3-O-(2′E,4′Z-decadienoyl)-20-O-acetylingenol,3-O-(2,3-dimethylbutanoyl)-13-O-dodecanoylingenol, were tentatively identified. The contents of most of these terpenoids were obviously decreased after processing with reductions of 6.66–95.25 %.Our findings could help us understand the chemical basis for the toxicity reduction of Gansui afforded by processing with vinegar. Further investigations are warranted to establish the relationship between processing-induced chemical changes and the reduction of toxicity of Gansui.

Keywords:

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol,158850-76-1,Natural Products, buy 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol , 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol supplier , purchase 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol , 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol cost , 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol manufacturer , order 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol , high purity 3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: