Camaric acid

CAS# 146450-83-1

Camaric acid

Catalog No. BCN1650----Order now to get a substantial discount!

Product Name & Size Price Stock
Camaric acid: 5mg $748 In Stock
Camaric acid: 10mg Please Inquire In Stock
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Quality Control of Camaric acid

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Chemical structure

Camaric acid

3D structure

Chemical Properties of Camaric acid

Cas No. 146450-83-1 SDF Download SDF
PubChem ID 91895465 Appearance Powder
Formula C35H52O6 M.Wt 568.8
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,2S,6S,10R,11S,14S,15R,18R,20S)-20-hydroxy-8,8,14,15,19,19-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-21-oxahexacyclo[18.2.2.01,18.02,15.05,14.06,11]tetracos-4-ene-11-carboxylic acid
SMILES CC=C(C)C(=O)OC1CC(CC2C1(CCC3(C2=CCC4C3(CCC5C46CCC(C5(C)C)(OC6)O)C)C)C(=O)O)(C)C
Standard InChIKey RSKOPEQHBSFOLQ-OTHZFUNLSA-N
Standard InChI InChI=1S/C35H52O6/c1-9-21(2)27(36)41-26-19-29(3,4)18-23-22-10-11-25-32(8,31(22,7)14-16-34(23,26)28(37)38)13-12-24-30(5,6)35(39)17-15-33(24,25)20-40-35/h9-10,23-26,39H,11-20H2,1-8H3,(H,37,38)/b21-9-/t23-,24-,25-,26+,31+,32+,33+,34-,35-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Camaric acid

The herbs of Lantana camara

Biological Activity of Camaric acid

Description1. Camaric acid, lantanilic acid, and oleanolic acid possess nematicidal activity, they exhibit 95%, 98% and 70% mortality respectively against root-knot nematode Meloidogyne incognita at 0.5% concentration. 2. Camaric acid shows antibacterial activity against Staphylococcus aureus and methicillin resistant S. aureus with IC50 values 8.74 and 8.09 uM, respectively, it also shows moderate antileishmanial activity and highly potent antitrypanosomal activity. 3. Camaric acid shows anticancer activity. 4. Camaric acid shows significant topical anti-inflammatory activity with IC50 value of 0.67 mg/ear in the assay of TPA mouse ear oedema model.
TargetsAntifection

Camaric acid Dilution Calculator

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Camaric acid Molarity Calculator

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Preparing Stock Solutions of Camaric acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7581 mL 8.7904 mL 17.5809 mL 35.1617 mL 43.9522 mL
5 mM 0.3516 mL 1.7581 mL 3.5162 mL 7.0323 mL 8.7904 mL
10 mM 0.1758 mL 0.879 mL 1.7581 mL 3.5162 mL 4.3952 mL
50 mM 0.0352 mL 0.1758 mL 0.3516 mL 0.7032 mL 0.879 mL
100 mM 0.0176 mL 0.0879 mL 0.1758 mL 0.3516 mL 0.4395 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Camaric acid

Oleanene constituents of Lantana cujabensis.[Pubmed:15158990]

Fitoterapia. 2004 Jun;75(3-4):327-31.

A new compound, 3beta,25-epoxy-3alpha-hydroxy-22beta-isobutanoyloxyolean-12-ene-28-oic acid (1), and two known triterpenoids lantanilic acid (2) and Camaric acid (3) were isolated from the stem and leaves of Lantana cujabensis. Their structures were elucidated by spectroscopic methods. The ethanol extracts did not show significant in vitro antiplasmodial activity against chloroquine-sensitive or resistant strains of Plasmodium falciparum.

Leishmanicidal Triterpenes from Lantana camara.[Pubmed:24827681]

Chem Biodivers. 2014 May;11(5):709-18.

Two new natural triterpenes, lantaninilic acid and lantoic acid, along with the known triterpenes lantadene A, and oleanolic, ursolic, betulinic, lantanolic, and Camaric acid, were obtained from the aerial parts of Lantana camara through bioassay-guided isolation, monitoring the in vitro antileishmanial activity against promastigotes of Leishmania major. Oleanolic acid (3), ursolic acid (4), lantadene A (5), and lantanilic acid (7) showed significant leishmanicidal activities with IC50 values of 53.0, 12.4, 20.4, and 21.3 muM, respectively. The IC50 value of ursolic acid (4; 12.4 muM) was found to be comparable with that of the standard drugs, pentamidine (IC50 15.0 muM) and amphotericin B (IC50 0.31 muM). The in vitro activities of L. camara and its constituents against promastigotes of Leishmania major are reported here for the first time.

Nematicidal natural products from the aerial parts of Lantana camara Linn.[Pubmed:16010828]

Nat Prod Res. 2005 Sep;19(6):609-13.

Lantanilic acid, Camaric acid and oleanolic acid possessing nematicidal activity were isolated from the methanolic extract of the aerial parts of Lantana camara Linn. through bio-assay guided fractionation. These compounds exhibited 98%, 95% and 70% mortality respectively against root-knot nematode Meloidogyne incognita at 0.5% concentration. Conventional nematicide furadan showed 100% mortality at this concentration.

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