Chamaemeloside

CAS# 173356-77-9

Chamaemeloside

Catalog No. BCN0010----Order now to get a substantial discount!

Product Name & Size Price Stock
Chamaemeloside: 5mg Please Inquire In Stock
Chamaemeloside: 10mg Please Inquire In Stock
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Quality Control of Chamaemeloside

Number of papers citing our products

Chemical structure

Chamaemeloside

Chemical Properties of Chamaemeloside

Cas No. 173356-77-9 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C27H28O14 M.Wt 576.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Synonyms Apigenin 7-[6''-(3-hydroxy-3-methylglutaryl)glucoside]
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Chamaemeloside

The herbs of Chamaemelum nobile

Biological Activity of Chamaemeloside

DescriptionChamaemeloside has hypoglycaemic activity.

Chamaemeloside Dilution Calculator

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Chamaemeloside Molarity Calculator

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Preparing Stock Solutions of Chamaemeloside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7346 mL 8.673 mL 17.3461 mL 34.6921 mL 43.3651 mL
5 mM 0.3469 mL 1.7346 mL 3.4692 mL 6.9384 mL 8.673 mL
10 mM 0.1735 mL 0.8673 mL 1.7346 mL 3.4692 mL 4.3365 mL
50 mM 0.0347 mL 0.1735 mL 0.3469 mL 0.6938 mL 0.8673 mL
100 mM 0.0173 mL 0.0867 mL 0.1735 mL 0.3469 mL 0.4337 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Chamaemeloside

Quantitative determination of seven chemical constituents and chemo-type differentiation of chamomiles using high-performance thin-layer chromatography.[Pubmed:25073627]

J Sep Sci. 2014 Oct;37(19):2797-804.

A simple and rapid high-performance thin-layer chromatographic method was developed for the separation and determination of six flavonoids (rutin, luteolin-7-O-beta-glucoside, Chamaemeloside, apigenin-7-O-beta-glucoside, luteolin, apigenin) and one coumarin, umbelliferone from chamomile plant samples and dietary supplements. The separation was achieved on amino silica stationary phase using dichloromethane/acetonitrile/ethyl formate/glacial acetic acid/formic acid (11:2.5:3:1.25:1.25 v/v/v/v/v) as the mobile phase. The quantitation of each compound was carried out using densitometric reflection/absorption mode at their respective absorbance maxima after postchromatographic derivatization using natural products reagent (1% w/v methanolic solution of diphenylboric acid-beta-ethylamino ester). The method was validated for specificity, limits of detection and quantification, precision (intra- and interday) and accuracy. The limits of detection and quantification were found to be in the range from 6-18 and 16-55 ng/band for six flavonoids and one coumarin, respectively. The intra- and interday precision was found to be <5% RSD and recovery of all the compounds was >90%. The data acquired from high-performance thin-layer chromatography was processed by principal component analysis using XLSTAT statistical software. Application of principal component analysis and agglomerative hierarchial clustering was successfully able to differentiate two chamomiles (German and Roman) and Chrysanthemum.

Quantitative determination of phenolic compounds by UHPLC-UV-MS and use of partial least-square discriminant analysis to differentiate chemo-types of Chamomile/Chrysanthemum flower heads.[Pubmed:24095803]

J Pharm Biomed Anal. 2014 Jan;88:278-88.

A new rapid UHPLC-UV-QTOF/MS method has been developed for the simultaneous analysis of nine phenolic compounds [(Z)-2-beta-d-glucopyranosyloxy-4-methoxycinnamic acid (cis-GMCA), chlorogenic acid, (E)-2-beta-d-glucopyranosyloxy-4-methoxycinnamic acid (trans-GMCA), quercetagetin-7-O-beta-d-glucopyranoside, luteolin-7-O-beta-d-glucoside, apigenin-7-O-beta-d-glucoside, Chamaemeloside, apigenin 7-O-(6''-O-acetyl-beta-d-glucopyranoside), apigenin] and one polyacetylene (tonghaosu) from the flower heads of Chamomile/Chrysanthemum samples. The chromatographic separation was achieved using a reversed phase C18 column with a mobile phase of water and acetonitrile, both containing 0.05% formic acid. The ten compounds were completely separated within 15min at a flow rate of 0.25mL/min with a 2muL injection volume. The different chemo-types of Chamomiles/Chrysanthemum displayed variations in the presence of chemical constituents. German Chamomile samples confirmed the presence of cis-GMCA, trans-GMCA, apigenin-7-O-beta-d-glucoside and tonghaosu as major constituents whereas Roman chamomile samples confirmed the presence of chamamaeloside and apigenin as major compounds. The Chrysanthemum morifolium samples showed the presence of luteolin-7-O-beta-d-glucose as the major compound. The method was applied for the analysis of various commercial products including capsules, tea bags, body and hair care products. LC-mass spectrometry with electrospray ionization (ESI) interface method is described for the evaluation of ten compounds in plant samples and commercial products. This method involved the detection of [M+Na](+) and [M+H](+) ions in the positive mode. Partial least squares discriminant analysis (PLS-DA) was used to visualize commercial samples quality and may be of value for discriminating between chamomile types and Chrysanthemum with regards to the relative content of individual constituents. The results indicated that the method is suitable as a quality control test for various Chamomile/Chrysanthemum samples and market products.

The aromatic and polyphenolic composition of Roman camomile tea.[Pubmed:14693217]

Fitoterapia. 2004 Jan;75(1):32-8.

The qualitative and quantitative composition of the main aromatic and polyphenolic constituents of infusion from Chamaemelum nobile flowers was examined. The camomile tea contained a large amount of polyphenolic compounds (340 mg/l), the most important being Chamaemeloside (155 mg/l). Only traces of essential oil were recovered in tea (7 mg/l).

Hypoglycaemic activity of an HMG-containing flavonoid glucoside, chamaemeloside, from Chamaemelum nobile.[Pubmed:9810266]

Planta Med. 1998 Oct;64(7):612-4.

The 3-hydroxy-3-methylglutaric acid (HMG) containing flavonoid glucoside Chamaemeloside, has been determined to have in vivo hypoglycaemic activity comparable to that of free HMG. An improved isolation scheme for obtaining Chamaemeloside from Chamaemelum nobile is presented.

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