Changnanic acid

CAS# 136040-44-3

Changnanic acid

2D Structure

Catalog No. BCX1818----Order now to get a substantial discount!

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Changnanic acid

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Chemical Properties of Changnanic acid

Cas No. 136040-44-3 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C30H44O4 M.Wt 468.67
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Changnanic acid Dilution Calculator

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Changnanic acid Molarity Calculator

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Preparing Stock Solutions of Changnanic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1337 mL 10.6685 mL 21.337 mL 42.6739 mL 53.3424 mL
5 mM 0.4267 mL 2.1337 mL 4.2674 mL 8.5348 mL 10.6685 mL
10 mM 0.2134 mL 1.0668 mL 2.1337 mL 4.2674 mL 5.3342 mL
50 mM 0.0427 mL 0.2134 mL 0.4267 mL 0.8535 mL 1.0668 mL
100 mM 0.0213 mL 0.1067 mL 0.2134 mL 0.4267 mL 0.5334 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Changnanic acid

Triterpenoids from Schisandra propinqua var. propinqua.[Pubmed:30452164]

Nat Prod Commun. 2016 Jul;11(7):925-929.

Four new triterpenoids, propindilactone T (1), propindilactone U (2), Changnanic acid 3-methyl ester (3) and schipropinic. acid (4), together with five known ones (5-9), were isolated and identified from the stems and leaves of Schisandra propinqua var. propinqua; their structures were determined based on spectroscopic and mass spectrometric analyses. The absolute configuration of 1 was confirmed by X-ray analysis. Compounds 1, 2, and 4-9 were tested for their cytotoxic activities against five human tumor cell lines; all were inactive except for 8, which showed weak activity against some of the cell lines.

New triterpenoids from Kadsura heteroclita and their cytotoxic activity.[Pubmed:16557460]

Planta Med. 2006 Apr;72(5):450-7.

Phytochemical investigations of the stem of Kadsura heteroclita (Roxb) Craib (Schizandraceae) resulted in the isolation and structure elucidation of six new triterpenoidal compounds named heteroclitalactones A-E (1-5) as well as heteroclic acid (6) and heteroclitalactone F (7), which was isolated for the first time from a natural source, and the six known compounds schisanlactone E (8), cycloartenone (9), schisandronic acid (10), nigranoic acid (11), Changnanic acid (12) and schisanlactone B (13), respectively. The structures of these compounds were characterized by extensive 1D and 2D NMR spectral analyses. The majority of these triterpenoids showed moderate cytotoxic activity against the human tumor cell lines Bel-7402, BGC-823, MCF-7 and HL-60. Among the compounds tested, heteroclitalactone D (4) showed the strongest cytotoxic activity against the HL-60 cells with an IC50 of 6.76 microM.

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