Embinin

CAS# 52589-13-6

Embinin

2D Structure

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3D structure

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Embinin

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Chemical Properties of Embinin

Cas No. 52589-13-6 SDF Download SDF
PubChem ID 3085014 Appearance Yellow powder
Formula C29H34O14 M.Wt 606.6
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 6-[(3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)chromen-4-one
SMILES CC1C(C(C(C(O1)OC2C(C(C(OC2C3=C(C=C4C(=C3O)C(=O)C=C(O4)C5=CC=C(C=C5)OC)OC)CO)O)O)O)O)O
Standard InChIKey OXTGLFRGBDFBHI-FFIOIDJNSA-N
Standard InChI InChI=1S/C29H34O14/c1-11-21(32)24(35)26(37)29(40-11)43-28-25(36)22(33)18(10-30)42-27(28)20-16(39-3)9-17-19(23(20)34)14(31)8-15(41-17)12-4-6-13(38-2)7-5-12/h4-9,11,18,21-22,24-30,32-37H,10H2,1-3H3/t11-,18-,21-,22-,24+,25+,26+,27?,28-,29?/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Embinin Dilution Calculator

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Preparing Stock Solutions of Embinin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.6485 mL 8.2427 mL 16.4853 mL 32.9707 mL 41.2133 mL
5 mM 0.3297 mL 1.6485 mL 3.2971 mL 6.5941 mL 8.2427 mL
10 mM 0.1649 mL 0.8243 mL 1.6485 mL 3.2971 mL 4.1213 mL
50 mM 0.033 mL 0.1649 mL 0.3297 mL 0.6594 mL 0.8243 mL
100 mM 0.0165 mL 0.0824 mL 0.1649 mL 0.3297 mL 0.4121 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Embinin

Phytochemistry and Ethnopharmacology of Some Medicinal Plants Used in the Kurdistan Region of Iraq.[Pubmed:27169177]

Nat Prod Commun. 2016 Mar;11(3):291-6.

The majority of Kurds inhabit a region that includes adjacent parts of Iran, Iraq, Syria and Turkey. This review shows that the traditional medicine is still used by Kurdish peoples and underlines the medicinal value of a great number of plants used locally. The medicinal uses include the treatment of a variety of diseases, ranging from simple stomach-ache to highly complicate male and female disorders; even sexual weakness and kidney stones are treated by plants. The majority of the plants that are used are for curing gastro-intestinal disorders and inflammation, followed by urinary tract disorders, skin burns, irritations and liver problems. In the last part of this paper, we also report the first results of our ongoing research project on the constituents of some uninvestigated Kurdish medicinal plants. The C-glycosylflavone Embinin, the alpha-methylene acyl derivative 6-tuliposide A, and the iridoids aucubin and ajugol were isolated for the first time from Iris persica, Tulipa systole and Verbascum calvum, respectively. These plants are traditionally used against inflammation, pain, and skin burns.

Chemotaxonomy of Hawaiian Anthurium cultivars based on multivariate analysis of phenolic metabolites.[Pubmed:25376013]

J Agric Food Chem. 2014 Nov 19;62(46):11323-34.

Thirty-six anthurium varieties, sampled from species and commercial cultivars, were extracted and profiled by liquid-chromatography-mass spectrometry (HPLC-MS). Three hundred fifteen compounds, including anthocyanins, flavonoid glycosides, and other phenolics, were detected from these extracts and used in chemotaxonomic analysis of the specimens. Hierarchical cluster analysis (HCA) revealed close chemical similarities between all the commercial standard cultivars, while tulip-shaped cultivars and species displayed much greater chemical variation. Principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA) supported the results from HCA and were used to identify key metabolites characteristic of standard and tulip cultivars and to identify chemical markers indicative of a particular ancestry. Discriminating metabolites included Embinin, 4, which was characteristic of standard-shaped spathes and indicated ancestry from Anthurium andraeanum, while isocytisoside 7-glucoside, 7, was found in the majority of tulip-shaped cultivars and suggested that Anthurium amnicola or Anthurium antioquiense had contributed to their pedigree.

Flavone C-glycosides from Anthurium andraeanum.[Pubmed:22816298]

Nat Prod Commun. 2012 Jun;7(6):747-8.

We describe here the isolation of three flavone 6-C-glycosides from the leaves of Anthurium andraeanum, The two new flavones were identified through detailed spectroscopic analysis as 4"'-(3,4-dimethoxycinnamoyl)-Embinin (2) and 4"'-ferruloyl-Embinin (3).

Flavone modulators of rat hepatic aryl hydrocarbon hydroxylase.[Pubmed:4059325]

Pharmacology. 1985;31(4):203-7.

The cytochrome P-450-dependent aryl hydrocarbon hydroxylase (AHH) metabolizes a wide variety of endogenous and exogenous compounds to nontoxic metabolites and/or toxic products. We have utilized a series of 18 flavone modulators of AHH to distinguish and probe for different cytochrome P-450 isozymes in liver microsomes from control and 3-methylcholanthrene (MC)-injected rats. some flavones (maackiain acetate, flavanone, mollisacacidin, Embinin, sciadopitysin) activated, while most of the tested compounds inhibited the MC-induced type of AHH. Although all flavones either inhibited or had little effect on the constitutive AHH in microsomes from control rats, the degree of inhibition varied greatly: some flavones (chrysin, chrysoeriol, baicalein, maackiain acetate, isoliquiritigenin, sciadopitysin) inhibited over 75% of the AHH. The various flavones we screened may prove useful in defining the cytochrome P-450 content of tissues and for probing the active sites of individual isozymes. The modulatory effects of the naturally occurring flavones assume additional importance in that they may be factors in animal and human responsiveness to cytochrome P-450 substrates.

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