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Epinortrachelogenin

CAS# 125072-69-7

Epinortrachelogenin

2D Structure

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Quality Control of Epinortrachelogenin

3D structure

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Epinortrachelogenin

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Chemical Properties of Epinortrachelogenin

Cas No. 125072-69-7 SDF Download SDF
PubChem ID 14159539 Appearance Powder
Formula C20H22O7 M.Wt 374.4
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3R,4S)-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
SMILES COC1=C(C=CC(=C1)CC2COC(=O)C2(CC3=CC(=C(C=C3)O)OC)O)O
Standard InChIKey ZITBJWXLODLDRH-VBKZILBWSA-N
Standard InChI InChI=1S/C20H22O7/c1-25-17-8-12(3-5-15(17)21)7-14-11-27-19(23)20(14,24)10-13-4-6-16(22)18(9-13)26-2/h3-6,8-9,14,21-22,24H,7,10-11H2,1-2H3/t14-,20+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Epinortrachelogenin

The barks of Cephalotaxus sinensis

Biological Activity of Epinortrachelogenin

DescriptionStandard reference

Protocol of Epinortrachelogenin

Structure Identification
Tetrahedron.1994 Apr 25;50(17):5203–5210.

Structural elucidation and conformational analysis of new lignan butenolides from the leaves of bupleurum salicifolium.[Reference: WebLink]


METHODS AND RESULTS:
From the leaves of Bupleurum salicifolium two new benzylidene-benzyl-γ-butyrolactone-type lignans salicifoline (2) and isosalicifoline (3) were isolated.
CONCLUSIONS:
The dibenzyl-butyrolactone (-)-Epinortrachelogenin (1) was also isolated and it is the first time than this lignan has been obtained from a natural source.

Journal of Wood Science, 2004 , 50 (6) :548-551.

Constituents from the roots of Taxus cuspidata[Reference: WebLink]


METHODS AND RESULTS:
The known propelargonidin, afzelechin-(48)-afzelechin (1), the known lignans 7-hydroxynortrachelogenin (2), Epinortrachelogenin (3), nortrachelogenin (4), hydroxymatairesinol (5), allohydroxymatairesinol (6), matairesinol (7), oxomatairesinol (8), and isotaxiresinol (9), and the known taxoids taxinine M (10), taxayuntin (11), and 10-deacetyltaxol (12), and 10-deacetylbaccatin III (13) were isolated from the roots of Taxus cuspidata (Japanese yew, Taxaceae).
CONCLUSIONS:
The propelargonidin was isolated from Taxus spp. for the first time, and was detected in the roots, bark, and twigs.

Epinortrachelogenin Dilution Calculator

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Preparing Stock Solutions of Epinortrachelogenin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6709 mL 13.3547 mL 26.7094 mL 53.4188 mL 66.7735 mL
5 mM 0.5342 mL 2.6709 mL 5.3419 mL 10.6838 mL 13.3547 mL
10 mM 0.2671 mL 1.3355 mL 2.6709 mL 5.3419 mL 6.6774 mL
50 mM 0.0534 mL 0.2671 mL 0.5342 mL 1.0684 mL 1.3355 mL
100 mM 0.0267 mL 0.1335 mL 0.2671 mL 0.5342 mL 0.6677 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Epinortrachelogenin

Structural elucidation and conformational analysis of new lignan butenolides from the leaves of bupleurum salicifolium.

Tetrahedron.1994 Apr 25;50(17):5203–5210.

From the leaves of Bupleurum salicifolium two new benzylidene-benzyl-γ-butyrolactone-type lignans salicifoline (2) and isosalicifoline (3) were isolated. The dibenzyl-butyrolactone (-)-Epinortrachelogenin (1) was also isolated and it is the first time than this lignan has been obtained from a natural source.

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