GarjasminCAS# 144868-43-9 |
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| Cas No. | 144868-43-9 | SDF | Download SDF |
| PubChem ID | 11138761 | Appearance | Powder |
| Formula | C11H12O5 | M.Wt | 224.2 |
| Type of Compound | Iridoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | COC(=O)C1=COC2C3C1C=CC3(CO2)O | ||
| Standard InChIKey | PYJMOWDBOPKFBI-SSQAQTMGSA-N | ||
| Standard InChI | InChI=1S/C11H12O5/c1-14-9(12)7-4-15-10-8-6(7)2-3-11(8,13)5-16-10/h2-4,6,8,10,13H,5H2,1H3/t6-,8-,10-,11-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Nauclea officinalis
| Description | 1. Garjasmine exhibits weak cytotoxic activity against KB and MCF-7 cell lines. |
Garjasmin Dilution Calculator
Garjasmin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.4603 mL | 22.3015 mL | 44.603 mL | 89.2061 mL | 111.5076 mL |
| 5 mM | 0.8921 mL | 4.4603 mL | 8.9206 mL | 17.8412 mL | 22.3015 mL |
| 10 mM | 0.446 mL | 2.2302 mL | 4.4603 mL | 8.9206 mL | 11.1508 mL |
| 50 mM | 0.0892 mL | 0.446 mL | 0.8921 mL | 1.7841 mL | 2.2302 mL |
| 100 mM | 0.0446 mL | 0.223 mL | 0.446 mL | 0.8921 mL | 1.1151 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Two new bioactive iridoids from Rothmannia wittii.[Pubmed:27431771]
Fitoterapia. 2016 Sep;113:97-101.
The first reported study of the isolation and identification of compounds from the bark and fruit of Rothmannia wittii yielded two new iridoids, 6beta-hydroxy-10-O-acetylgenipin (1) and 10-O-acetylmacrophyllide (2) together with six known iridoids; 6beta-hydroxygenipin (3), genipin (4), Garjasmine (5), cerbinal (6), and mixture of beta-gardiol (7) and alpha-gardiol (8); benzoic acid (9); vanillic acid (10); and stigmasterol (11). Their structures were elucidated by spectroscopic methods. Iridoid 1 showed antimycobacterial activity against Mycobacterium tuberculosis with a MIC value of 12.50mug/mL. Iridoid 2 showed cytotoxicity against the NCI-H187 cancer cell line with an IC50 value of 6.82mug/mL. In addition, 2 and 5 exhibited weak cytotoxic activity against KB and MCF-7 cell lines, while 4 was active against the NCI-H187 cancer cell line.
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