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24-Methylenecycloartanone

CAS# 1449-08-7

24-Methylenecycloartanone

2D Structure

Catalog No. BCN7244----Order now to get a substantial discount!

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Quality Control of 24-Methylenecycloartanone

3D structure

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24-Methylenecycloartanone

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Chemical Properties of 24-Methylenecycloartanone

Cas No. 1449-08-7 SDF Download SDF
PubChem ID 3083719 Appearance Powder
Formula C31H50O M.Wt 438.74
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(C)C(=C)CCC(C)C1CCC2(C1(CCC34C2CCC5C3(C4)CCC(=O)C5(C)C)C)C
Standard InChIKey AEAWOMODYBIREN-KXDMVREESA-N
Standard InChI InChI=1S/C31H50O/c1-20(2)21(3)9-10-22(4)23-13-15-29(8)25-12-11-24-27(5,6)26(32)14-16-30(24)19-31(25,30)18-17-28(23,29)7/h20,22-25H,3,9-19H2,1-2,4-8H3/t22?,23-,24?,25?,28-,29+,30-,31+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 24-Methylenecycloartanone

The rhizomes of Polygonum bistorta.

Biological Activity of 24-Methylenecycloartanone

Description24-Methylenecycloartanone is a natural product from Polygonum bistorta.

Protocol of 24-Methylenecycloartanone

Structure Identification
Phytochemistry. 2005 Oct;66(19):2304-8.

Cycloartane type triterpenoids from the rhizomes of Polygonum bistorta.[Pubmed: 16112695 ]


METHODS AND RESULTS:
Two new compounds, 24(E)-ethylidenecycloartanone (1) and 24(E)-ethylidenecycloartan-3alpha-ol (2) were isolated from the rhizomes of Polygonum bistorta, together with seven known compounds viz., cycloartane-3,24-dione (3), 24-Methylenecycloartanone (4), gamma-sitosterol (5), beta-sitosterol (6), beta-sitosterone (7), friedelin (8) and 3beta-friedelinol (9).
CONCLUSIONS:
All the cycloartane type triterpenoids, compounds 7 and 8 are reported for the first time from this plant. A combination of 1D and 2D NMR spectroscopy and MS were mainly used to elucidate the structures of the new compounds 1 and 2.

24-Methylenecycloartanone Dilution Calculator

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24-Methylenecycloartanone Molarity Calculator

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Preparing Stock Solutions of 24-Methylenecycloartanone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2793 mL 11.3963 mL 22.7925 mL 45.5851 mL 56.9814 mL
5 mM 0.4559 mL 2.2793 mL 4.5585 mL 9.117 mL 11.3963 mL
10 mM 0.2279 mL 1.1396 mL 2.2793 mL 4.5585 mL 5.6981 mL
50 mM 0.0456 mL 0.2279 mL 0.4559 mL 0.9117 mL 1.1396 mL
100 mM 0.0228 mL 0.114 mL 0.2279 mL 0.4559 mL 0.5698 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 24-Methylenecycloartanone

Cycloartane type triterpenoids from the rhizomes of Polygonum bistorta.[Pubmed:16112695]

Phytochemistry. 2005 Oct;66(19):2304-8.

Two new compounds, 24(E)-ethylidenecycloartanone (1) and 24(E)-ethylidenecycloartan-3alpha-ol (2) were isolated from the rhizomes of Polygonum bistorta, together with seven known compounds viz., cycloartane-3,24-dione (3), 24-Methylenecycloartanone (4), gamma-sitosterol (5), beta-sitosterol (6), beta-sitosterone (7), friedelin (8) and 3beta-friedelinol (9). All the cycloartane type triterpenoids, compounds 7 and 8 are reported for the first time from this plant. A combination of 1D and 2D NMR spectroscopy and MS were mainly used to elucidate the structures of the new compounds 1 and 2.

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