H-Asp(OtBu)-OHCAS# 3057-74-7 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 3057-74-7 | SDF | Download SDF |
| PubChem ID | 102930 | Appearance | Powder |
| Formula | C8H15NO4 | M.Wt | 189.2 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-amino-4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid | ||
| SMILES | CC(C)(C)OC(=O)CC(C(=O)O)N | ||
| Standard InChIKey | MXWMFBYWXMXRPD-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C8H15NO4/c1-8(2,3)13-6(10)4-5(9)7(11)12/h5H,4,9H2,1-3H3,(H,11,12) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
H-Asp(OtBu)-OH Dilution Calculator
H-Asp(OtBu)-OH Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.2854 mL | 26.4271 mL | 52.8541 mL | 105.7082 mL | 132.1353 mL |
| 5 mM | 1.0571 mL | 5.2854 mL | 10.5708 mL | 21.1416 mL | 26.4271 mL |
| 10 mM | 0.5285 mL | 2.6427 mL | 5.2854 mL | 10.5708 mL | 13.2135 mL |
| 50 mM | 0.1057 mL | 0.5285 mL | 1.0571 mL | 2.1142 mL | 2.6427 mL |
| 100 mM | 0.0529 mL | 0.2643 mL | 0.5285 mL | 1.0571 mL | 1.3214 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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H-Asp(OtBu)-OH
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Synthesis of the C-terminal half of thymosin alpha 1 by the polymeric reagent method.[Pubmed:6832888]
Int J Pept Protein Res. 1983 Feb;21(2):145-54.
In this report we further show the utility and efficiency of polymer-bound 1-hydroxybenzotriazole (PHBT) as an almost ideal support for the polymeric reagent method of peptide synthesis. This was demonstrated by the synthesis of thymosin alpha 1 (15-28), in which two suitably blocked segments, Boc-Asp (OtBu)-Leu-Lys (2Cz)-Glu (OBzl)-Lys (2Cz)-Lys (2Cz)-OH (3) and Boc-Glu (OBzl)-Val-Val-Glu (OBzl)-Glu (OBzl)-Ala-Glu (OBzl)-Asn-OBzl (2), were prepared entirely by utilizing PHBT activation for each coupling step. After appropriate deblocking of 2, segments 2 and 3 were coupled by the DCC-HOBT method, followed by complete deblocking and ion-exchange chromatographic purification, affording the C-terminal half of thymosin alpha 1, H-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH (1).
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