HannokinolCAS# 79120-40-4 |
- (+)-Hannokinol
Catalog No.:BCN9664
CAS No.:408324-76-5
- meso-Hannokinol
Catalog No.:BCN0540
CAS No.:79055-11-1
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 79120-40-4 | SDF | Download SDF |
| PubChem ID | 14427394 | Appearance | Powder |
| Formula | C19H24O4 | M.Wt | 316.4 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Synonyms | 1,7-Bis(4-hydroxyphenyl)-3,5-heptanediol | ||
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1,7-bis(4-hydroxyphenyl)heptane-3,5-diol | ||
| SMILES | C1=CC(=CC=C1CCC(CC(CCC2=CC=C(C=C2)O)O)O)O | ||
| Standard InChIKey | GZVIQGVWSNEONZ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C19H24O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-4,7-10,18-23H,5-6,11-13H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | (+)-Hannokinol and MESO-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM. |
| Targets | NO |
| In vitro | Inhibitory constituents of lipopolysaccharide-induced nitric oxide production in BV2 microglia isolated from Amomum tsao-ko.[Pubmed: 18523923 ]Planta Med. 2008 Jun;74(8):867-9.A methanolic extract of the fruits of AMOMUM TSAO-KO (Zingiberaceae) significantly attenuated nitric oxide production in lipopolysaccharide-simulated BV2 microglia. |
| Structure Identification | Chinese Journal of Experimental Traditional Medical Formulae, 2015 , 21 (3) :37-40.Identification of Chemical Constituents Occurring in Leaves of Alpinia officinarum[Reference: WebLink]The current study aimed to identify the chemical constituents occurring in the leaves of Alpinia officinarum. |
Hannokinol Dilution Calculator
Hannokinol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.1606 mL | 15.8028 mL | 31.6056 mL | 63.2111 mL | 79.0139 mL |
| 5 mM | 0.6321 mL | 3.1606 mL | 6.3211 mL | 12.6422 mL | 15.8028 mL |
| 10 mM | 0.3161 mL | 1.5803 mL | 3.1606 mL | 6.3211 mL | 7.9014 mL |
| 50 mM | 0.0632 mL | 0.3161 mL | 0.6321 mL | 1.2642 mL | 1.5803 mL |
| 100 mM | 0.0316 mL | 0.158 mL | 0.3161 mL | 0.6321 mL | 0.7901 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Inhibitory constituents of lipopolysaccharide-induced nitric oxide production in BV2 microglia isolated from Amomum tsao-ko.[Pubmed:18523923]
Planta Med. 2008 Jun;74(8):867-9.
A methanolic extract of the fruits of AMOMUM TSAO-KO (Zingiberaceae) significantly attenuated nitric oxide production in lipopolysaccharide-simulated BV2 microglia. Two new bicyclic nonanes characterized as 6,7-dihydroxy-indan-4-carbaldehyde ( 1) and 6-hydroxy-indan-4-carbaldehyde ( 2) were isolated with the eleven known compounds 6,7-dihydroxy-3,7-dimethyloct-2-enoic acid ( 3), tsaokoin ( 4), isotsaokoin ( 5), 8-oxogeraniol ( 6), P-menth-1-ene-5,6-diol ( 7), 3alpha-hydroxycarvotagenone ( 8), tsaokoarylone ( 9), 1,7-bis(4-hydroxy-3-methoxyphenyl)-4,6-heptadien-3one ( 10), (+)-Hannokinol ( 11), MESO-Hannokinol ( 12) and hannokinin ( 13), from the fruits of A. TSAO-KO using bioactivity-guided fractionation. All thirteen compounds significantly inhibited lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM.
