Hecubine

CAS# 62874-52-6

Hecubine

Catalog No. BCN7467----Order now to get a substantial discount!

Product Name & Size Price Stock
Hecubine: 5mg $886 In Stock
Hecubine: 10mg Please Inquire In Stock
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Quality Control of Hecubine

Number of papers citing our products

Chemical structure

Hecubine

3D structure

Chemical Properties of Hecubine

Cas No. 62874-52-6 SDF Download SDF
PubChem ID 11438319 Appearance Oil
Formula C20H26N2O M.Wt 310.44
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCC12CCC3=C(CCN(C1)CC4C2O4)C5=CC=CC=C5N3C
Standard InChIKey XUDAGNVXWJRKJD-AQNXPRMDSA-N
Standard InChI InChI=1S/C20H26N2O/c1-3-20-10-8-17-15(14-6-4-5-7-16(14)21(17)2)9-11-22(13-20)12-18-19(20)23-18/h4-7,18-19H,3,8-13H2,1-2H3/t18-,19-,20+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Hecubine

The stems and leaves of Ervatamia hainanensis.

Biological Activity of Hecubine

DescriptionHecubine is a natural product from Ervatamia hainanensis.

Protocol of Hecubine

Structure Identification
Journal of Mountain Agriculture & Biology, 2011 , 30 (2) :177-180.

Isolation and Identification of Indole Alkaloid from Ervatamia hainanensis[Reference: WebLink]

Four compounds were isolated from the crude alkaloids of Ervatamia hainanensis.by classic phytochemical techniques.Their structures were identified as Vacancies,Coronaridine,(+)-Hecubine,and(+)-Voaphylline using spectroscopic methods,including 1H-NMR,13C-NMR,DEPT,and ESI-MS,and with help of the corresponding literatures.

Hecubine Dilution Calculator

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Hecubine Molarity Calculator

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Preparing Stock Solutions of Hecubine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2212 mL 16.1062 mL 32.2123 mL 64.4247 mL 80.5309 mL
5 mM 0.6442 mL 3.2212 mL 6.4425 mL 12.8849 mL 16.1062 mL
10 mM 0.3221 mL 1.6106 mL 3.2212 mL 6.4425 mL 8.0531 mL
50 mM 0.0644 mL 0.3221 mL 0.6442 mL 1.2885 mL 1.6106 mL
100 mM 0.0322 mL 0.1611 mL 0.3221 mL 0.6442 mL 0.8053 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Hecubine

Synthesis of vinca alkaloids and related compounds. 100. Stereoselective oxidation reactions of compounds with the aspidospermane and quebrachamine ring system. First synthesis of some alkaloids containing the epoxy ring.[Pubmed:12375951]

J Org Chem. 2002 Oct 18;67(21):7255-60.

The first syntheses of the alkaloids (-)-mehranine (3), (+)-voaphylline/conoflorine (4), (+)-N(a)-methylvoaphylline/Hecubine (5), and (-)-lochnericine (2) were achieved by stereoselective epoxidation starting from (-)-tabersonine (1), through intermediates with the aspidospermane and quebrachamine skeleton.

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