Voafinidine

CAS# 180059-77-2

Voafinidine

Catalog No. BCN6738----Order now to get a substantial discount!

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Voafinidine: 5mg $960 In Stock
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Quality Control of Voafinidine

Number of papers citing our products

Chemical structure

Voafinidine

3D structure

Chemical Properties of Voafinidine

Cas No. 180059-77-2 SDF Download SDF
PubChem ID 11121012 Appearance Powder
Formula C20H28N2O2 M.Wt 328.45
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CCC12CCC3=C(CCN(C1)CC(C2O)O)C4=CC=CC=C4N3C
Standard InChIKey LZWQFKGUQLBGKC-ZCNNSNEGSA-N
Standard InChI InChI=1S/C20H28N2O2/c1-3-20-10-8-17-15(14-6-4-5-7-16(14)21(17)2)9-11-22(13-20)12-18(23)19(20)24/h4-7,18-19,23-24H,3,8-13H2,1-2H3/t18-,19+,20-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Voafinidine

The herbs of Tabernaemontana divaricata

Biological Activity of Voafinidine

DescriptionVoafinidine is a natural product from Tabernaemontana divaricata.

Protocol of Voafinidine

Structure Identification
Org Biomol Chem. 2003 Apr 21;1(8):1292-7.

Biologically active indole and bisindole alkaloids from Tabernaemontana divaricata.[Pubmed: 12929658]


METHODS AND RESULTS:
The ethanol extract of the leaves of Tabernaemontana divaricata (double flower variety) provided a total of 23 alkaloids, including the new aspidosperma alkaloids, taberhanine, voafinine, N-methylvoafinine, Voafinidine, voalenine and the new bisindole alkaloid, conophyllinine in addition to the previously known, biologically active bisindole, conophylline and its congener, conofoline. The structures of the new alkaloids were established by spectroscopic methods.
CONCLUSIONS:
The preparation and characterization of the corresponding quinones of the biologically active bisindoles are also described in relation to a structure-activity study of these compounds with respect to their action in stimulating insulin expression.

Natural Product Letters, 1996 , 8 (1) :49-53.

Voafinidine and Voalenine, Novel Indoles of the Aspidosperma-type from Tabernaemontana[Reference: WebLink]

Novel indole alkaloids of the aspidosperma-type, viz., Voafinidine and voalenine were obtained in minor amounts from the leaf extract of Tabernaemontana divaricata (double flower variety). The structures of these alkaloids were elucidated by spectral methods.

Voafinidine Dilution Calculator

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Voafinidine Molarity Calculator

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Preparing Stock Solutions of Voafinidine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.0446 mL 15.223 mL 30.446 mL 60.8921 mL 76.1151 mL
5 mM 0.6089 mL 3.0446 mL 6.0892 mL 12.1784 mL 15.223 mL
10 mM 0.3045 mL 1.5223 mL 3.0446 mL 6.0892 mL 7.6115 mL
50 mM 0.0609 mL 0.3045 mL 0.6089 mL 1.2178 mL 1.5223 mL
100 mM 0.0304 mL 0.1522 mL 0.3045 mL 0.6089 mL 0.7612 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Voafinidine

Biologically active indole and bisindole alkaloids from Tabernaemontana divaricata.[Pubmed:12929658]

Org Biomol Chem. 2003 Apr 21;1(8):1292-7.

The ethanol extract of the leaves of Tabernaemontana divaricata (double flower variety) provided a total of 23 alkaloids, including the new aspidosperma alkaloids, taberhanine, voafinine, N-methylvoafinine, Voafinidine, voalenine and the new bisindole alkaloid, conophyllinine in addition to the previously known, biologically active bisindole, conophylline and its congener, conofoline. The structures of the new alkaloids were established by spectroscopic methods. The preparation and characterization of the corresponding quinones of the biologically active bisindoles are also described in relation to a structure-activity study of these compounds with respect to their action in stimulating insulin expression.

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