Lucidone B

CAS# 97653-93-5

Lucidone B

Catalog No. BCN8242----Order now to get a substantial discount!

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Quality Control of Lucidone B

Number of papers citing our products

Chemical structure

Lucidone B

3D structure

Chemical Properties of Lucidone B

Cas No. 97653-93-5 SDF Download SDF
PubChem ID 14109411 Appearance Powder
Formula C24H32O5 M.Wt 400.51
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 17-acetyl-7-hydroxy-4,4,10,13,14-pentamethyl-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthrene-3,11,15-trione
SMILES CC(=O)C1CC(=O)C2(C1(CC(=O)C3=C2C(CC4C3(CCC(=O)C4(C)C)C)O)C)C
Standard InChIKey AJULRUMEMZKBQI-UHFFFAOYSA-N
Standard InChI InChI=1S/C24H32O5/c1-12(25)13-9-18(29)24(6)20-14(26)10-16-21(2,3)17(28)7-8-22(16,4)19(20)15(27)11-23(13,24)5/h13-14,16,26H,7-11H2,1-6H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Lucidone B

The fruit body of Ganoderma lucidum

Protocol of Lucidone B

Structure Identification
Chinese Journal of Medicinal Chemistry, 2013 (2) :115-119.

Study on the chemical constituents from Ganoderma tropicum.[Reference: WebLink]

Lingzhi" is Chinese generic name for basiocarps of Ganoderma,which was widely distributed and well-studied.Ganoderma genera is used widely as a health supplement and "herbal" medicine.Ganoderma tropicum(Jungh.) Bres.is the main wild Ganoderma resources distributed in tropical area of China,and its natural products and their biological activities are still not reported.
METHODS AND RESULTS:
In this paper,we reported the isolation,structural elucidation of natural compounds from the fruiting bodies of G.tropicum for the first time.During our investigation on G.tropicum,ten compounds were isolated.
CONCLUSIONS:
Their structures were identified as 3β,7β-dihydroxy-11,15,23-trioxo-lanost-8,16-dien-26-oic acid methyl ester(1),ganoderenic acid I(2),methyl ganoderate B(3),Lucidone B(4),lucidone A(5),ganoderenic acid H(6),methyl ganoderate H(7),24R-ergosta-7,22-diene-3,5,6-triol(8),22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol(9),ergosta-7,22-dien-3β-ol(10) by NMR spectra as well as comparison with those reported in the literatures.

Lucidone B Dilution Calculator

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Preparing Stock Solutions of Lucidone B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4968 mL 12.4841 mL 24.9682 mL 49.9363 mL 62.4204 mL
5 mM 0.4994 mL 2.4968 mL 4.9936 mL 9.9873 mL 12.4841 mL
10 mM 0.2497 mL 1.2484 mL 2.4968 mL 4.9936 mL 6.242 mL
50 mM 0.0499 mL 0.2497 mL 0.4994 mL 0.9987 mL 1.2484 mL
100 mM 0.025 mL 0.1248 mL 0.2497 mL 0.4994 mL 0.6242 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Lucidone B

Nortriterpenoids from the Fruiting Bodies of the Mushroom Ganoderma resinaceum.[Pubmed:28657576]

Molecules. 2017 Jun 28;22(7). pii: molecules22071073.

Ganoderma resinaceum is usually used as ethnomedicine for immune-regulation, hyperglycemia, and liver disease. To date, only a few chemical constituents have been reported from G. resinaceum. In this study, fifteen nortriterpenoids including six new nortriterpenoids (1-6) and nine known analogs (7-15), were separated and purified from the fruiting bodies of G. resinaceum. New compounds were identified as lucidone I (1), lucidone J (2), lucidone K (3), lucidone I (4), ganosineniol B (5), and ganosineniol C (6), based on analysis of extensive spectroscopic data (high resolution mass spectrometry (HRMS), nuclear magnetic resonance (NMR), infrared (IR), and ultraviolet (UV)). The known compounds were assigned as lucidone A (7), Lucidone B (8), lucidone H (9), lucidone E (10), lucidone F (11), lucidone D (12), lucidone C (13), ganoderense F (14), and ganosineniol A (15), by comparing their spectroscopic data with those reported in the literature. Compounds 3, 4, and 7-13 were examined for alpha-glucosidase inhibitory activity and display no significant activity, but the finding may support that the side chain of ganoderma triterpenoids played an important role in alpha-glucosidase inhibitory activity.

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