N-BenzyloleamideCAS# 101762-87-2 |
Quality Control & MSDS
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| Cas No. | 101762-87-2 | SDF | Download SDF |
| PubChem ID | 49865534 | Appearance | Powder |
| Formula | C25H41NO | M.Wt | 371.6 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Synonyms | Macamide Impurity 2 | ||
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (Z)-N-benzyloctadec-9-enamide | ||
| SMILES | CCCCCCCCC=CCCCCCCCC(=O)NCC1=CC=CC=C1 | ||
| Standard InChIKey | QHXGFOCPQQADIF-KTKRTIGZSA-N | ||
| Standard InChI | InChI=1S/C25H41NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-25(27)26-23-24-20-17-16-18-21-24/h9-10,16-18,20-21H,2-8,11-15,19,22-23H2,1H3,(H,26,27)/b10-9- | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. N-benzyloleamide has pharmaceutical property against exercise-induced fatigue, and this effect can be explained by the modulated energy metabolism and improved antioxidant status. |
| Targets | SOD |
N-Benzyloleamide Dilution Calculator
N-Benzyloleamide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6911 mL | 13.4553 mL | 26.9107 mL | 53.8213 mL | 67.2766 mL |
| 5 mM | 0.5382 mL | 2.6911 mL | 5.3821 mL | 10.7643 mL | 13.4553 mL |
| 10 mM | 0.2691 mL | 1.3455 mL | 2.6911 mL | 5.3821 mL | 6.7277 mL |
| 50 mM | 0.0538 mL | 0.2691 mL | 0.5382 mL | 1.0764 mL | 1.3455 mL |
| 100 mM | 0.0269 mL | 0.1346 mL | 0.2691 mL | 0.5382 mL | 0.6728 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effects of macamides on endurance capacity and anti-fatigue property in prolonged swimming mice.[Pubmed:26453017]
Pharm Biol. 2016;54(5):827-34.
CONTEXT: Lepidium meyenii Walp. (Brassicaceae), most commonly known as "maca", has been used as a food or folk medicine to improve vitality in Peru. Previous research demonstrated that lipid-soluble extract from maca improved swimming endurance capacity. Macamides are considered the typical lipid-soluble markers for maca and proved to have several pharmacological properties, such as improving sexual performance and neuroprotective activies. OBJECTIVE: The present study investigates the effects of macamides on endurance capacity and anti-fatigue property in prolonged swimming mice. MATERIALS AND METHODS: The Balb/c mice were divided into seven groups: a control group, low-dose groups of N-benzyllinoleamide, N-Benzyloleamide, and N-benzylpalmitamide, high-dose groups of these macamides. The macamides groups received the commercial products (12 and 40 mg/kg, ig), while the control group received vehicle for 21 d. On the 14th day, the mice were given the weight-loaded swimming test. On the 21st day, the mice were sacrificed immediately after 90 min swimming, and some biochemical parameters were measured. RESULTS AND DISCUSSION: Compared with the control group, exhaustive swimming time was significantly prolonged in high-dose group of N-Benzyloleamide (p < 0.05); the levels of lactic acid (LD), blood ammonia (BA), and lactate dehydrogenase (LDH) were significantly decreased (p < 0.05), whereas the levels of liver glycogen (LG) and non-esterified fatty acid (NEFA) were significantly increased (p < 0.05) in high-dose group of N-Benzyloleamide. The malondialdehyde (MDA) contents in the brain, muscle, and liver were significantly decreased (p < 0.05), whereas superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) activities in the brain, muscle, and liver were significantly increased in high-dose group of N-Benzyloleamide (p < 0.05). CONCLUSION: The results indicate that N-Benzyloleamide has pharmaceutical property against exercise-induced fatigue, and this effect can be explained by the modulated energy metabolism and improved antioxidant status.
