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N1,N5,N10-Tri-p-coumaroylspermidine

CAS# 131086-78-7

N1,N5,N10-Tri-p-coumaroylspermidine

Catalog No. BCN9283----Order now to get a substantial discount!

Product Name & Size Price Stock
N1,N5,N10-Tri-p-coumaroylspermidine: 5mg $903 In Stock
N1,N5,N10-Tri-p-coumaroylspermidine: 10mg Please Inquire In Stock
N1,N5,N10-Tri-p-coumaroylspermidine: 20mg Please Inquire Please Inquire
N1,N5,N10-Tri-p-coumaroylspermidine: 50mg Please Inquire Please Inquire
N1,N5,N10-Tri-p-coumaroylspermidine: 100mg Please Inquire Please Inquire
N1,N5,N10-Tri-p-coumaroylspermidine: 200mg Please Inquire Please Inquire
N1,N5,N10-Tri-p-coumaroylspermidine: 500mg Please Inquire Please Inquire
N1,N5,N10-Tri-p-coumaroylspermidine: 1000mg Please Inquire Please Inquire

Quality Control of N1,N5,N10-Tri-p-coumaroylspermidine

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Chemical structure

N1,N5,N10-Tri-p-coumaroylspermidine

3D structure

Chemical Properties of N1,N5,N10-Tri-p-coumaroylspermidine

Cas No. 131086-78-7 SDF Download SDF
PubChem ID 72739177 Appearance Powder
Formula C34H37N3O6 M.Wt 583.7
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 3-(4-hydroxyphenyl)-N-[4-[3-(4-hydroxyphenyl)prop-2-enoyl-[3-[3-(4-hydroxyphenyl)prop-2-enoylamino]propyl]amino]butyl]prop-2-enamide
SMILES C1=CC(=CC=C1C=CC(=O)NCCCCN(CCCNC(=O)C=CC2=CC=C(C=C2)O)C(=O)C=CC3=CC=C(C=C3)O)O
Standard InChIKey PFDVWJCSCYDRMZ-UHFFFAOYSA-N
Standard InChI InChI=1S/C34H37N3O6/c38-29-13-4-26(5-14-29)10-19-32(41)35-22-1-2-24-37(34(43)21-12-28-8-17-31(40)18-9-28)25-3-23-36-33(42)20-11-27-6-15-30(39)16-7-27/h4-21,38-40H,1-3,22-25H2,(H,35,41)(H,36,42)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

N1,N5,N10-Tri-p-coumaroylspermidine Dilution Calculator

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N1,N5,N10-Tri-p-coumaroylspermidine Molarity Calculator

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Preparing Stock Solutions of N1,N5,N10-Tri-p-coumaroylspermidine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7132 mL 8.566 mL 17.1321 mL 34.2642 mL 42.8302 mL
5 mM 0.3426 mL 1.7132 mL 3.4264 mL 6.8528 mL 8.566 mL
10 mM 0.1713 mL 0.8566 mL 1.7132 mL 3.4264 mL 4.283 mL
50 mM 0.0343 mL 0.1713 mL 0.3426 mL 0.6853 mL 0.8566 mL
100 mM 0.0171 mL 0.0857 mL 0.1713 mL 0.3426 mL 0.4283 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on N1,N5,N10-Tri-p-coumaroylspermidine

Inhibitory effects on HIV-1 protease of tri-p-coumaroylspermidine from Artemisia caruifolia and related amides.[Pubmed:11456103]

Chem Pharm Bull (Tokyo). 2001 Jul;49(7):915-7.

From a methanol extract of Artemisia caruifolia, which showed a moderate inhibitory activity on HIV-1 protease in a preliminary screening, N1,N5,N10-Tri-p-coumaroylspermidine and three dicaffeoylquinic acids were isolated. The former compound was found to appreciably inhibit HIV-1 protease. Of related amides which were chemically synthesized, N1,N5,N10,N14-tetra-p-coumaroylspermine and N1,N4,N7,N10,N13-penta-p-coumaroylte-traethylenepentamine inhibited HIV-1 protease more potently than N1,N5,N10-Tri-p-coumaroylspermidine.

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