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N1,N10-Bis(p-coumaroyl)spermidine

CAS# 114916-05-1

N1,N10-Bis(p-coumaroyl)spermidine

2D Structure

Catalog No. BCN6027----Order now to get a substantial discount!

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N1,N10-Bis(p-coumaroyl)spermidine: 5mg $903 In Stock
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Quality Control of N1,N10-Bis(p-coumaroyl)spermidine

3D structure

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N1,N10-Bis(p-coumaroyl)spermidine

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Chemical Properties of N1,N10-Bis(p-coumaroyl)spermidine

Cas No. 114916-05-1 SDF Download SDF
PubChem ID 15270795 Appearance Powder
Formula C25H31N3O4 M.Wt 437.5
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (E)-3-(4-hydroxyphenyl)-N-[4-[3-[[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]propylamino]butyl]prop-2-enamide
SMILES C1=CC(=CC=C1C=CC(=O)NCCCCNCCCNC(=O)C=CC2=CC=C(C=C2)O)O
Standard InChIKey QYBCBMVQSCJMSA-VOMDNODZSA-N
Standard InChI InChI=1S/C25H31N3O4/c29-22-10-4-20(5-11-22)8-14-24(31)27-18-2-1-16-26-17-3-19-28-25(32)15-9-21-6-12-23(30)13-7-21/h4-15,26,29-30H,1-3,16-19H2,(H,27,31)(H,28,32)/b14-8+,15-9+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of N1,N10-Bis(p-coumaroyl)spermidine

The herbs of Exochorda racemosa

Protocol of N1,N10-Bis(p-coumaroyl)spermidine

Structure Identification
Phytochemistry, 1998, 47(3):375-387.

The biosynthesis of lunarine in seeds of Lunaria annua.[Reference: WebLink]


METHODS AND RESULTS:
Using an optimized precursor feeding system, the biosynthesis of the alkaloid lunarine in Lunaria annua seeds was investigated. The synthesis of radioactively labelled precursors for the application experiments is described. Lunarine was shown to be synthesized by stereo-selective phenol-oxidative coupling of N1,N10-Bis(p-coumaroyl)spermidine. p-Coumaric acid for the biosynthesis of this dimer is formed from L-phenylalanine via trans-cinnamic acid. The polyamine moiety of lunarine, spermidine, and its immediate precursor putrescine are preferentially synthesized from arginine.
CONCLUSIONS:
Enzyme studies with microsomes of Lunaria annua seeds indicated that a cytochrome P-450 enzyme might be responsible for the phenol-oxidative coupling of N1,N10-bis (p-coumaroyl)spermidine yielding the hexahydrodibenzofuran ring of lunarine.

N1,N10-Bis(p-coumaroyl)spermidine Dilution Calculator

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N1,N10-Bis(p-coumaroyl)spermidine Molarity Calculator

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Preparing Stock Solutions of N1,N10-Bis(p-coumaroyl)spermidine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2857 mL 11.4286 mL 22.8571 mL 45.7143 mL 57.1429 mL
5 mM 0.4571 mL 2.2857 mL 4.5714 mL 9.1429 mL 11.4286 mL
10 mM 0.2286 mL 1.1429 mL 2.2857 mL 4.5714 mL 5.7143 mL
50 mM 0.0457 mL 0.2286 mL 0.4571 mL 0.9143 mL 1.1429 mL
100 mM 0.0229 mL 0.1143 mL 0.2286 mL 0.4571 mL 0.5714 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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