NVP-QAV680

CAS# 872365-16-7

NVP-QAV680

Catalog No. BCC5508----Order now to get a substantial discount!

Product Name & Size Price Stock
NVP-QAV680: 5mg $380 In Stock
NVP-QAV680: 10mg Please Inquire In Stock
NVP-QAV680: 20mg Please Inquire Please Inquire
NVP-QAV680: 50mg Please Inquire Please Inquire
NVP-QAV680: 100mg Please Inquire Please Inquire
NVP-QAV680: 200mg Please Inquire Please Inquire
NVP-QAV680: 500mg Please Inquire Please Inquire
NVP-QAV680: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of NVP-QAV680

Number of papers citing our products

Chemical structure

NVP-QAV680

3D structure

Chemical Properties of NVP-QAV680

Cas No. 872365-16-7 SDF Download SDF
PubChem ID 11508736 Appearance Powder
Formula C18H18N2O4S M.Wt 358.41
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in DMSO
Chemical Name 2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[2,3-b]pyridin-3-yl]acetic acid
SMILES CC1=C(C2=C(N1CC3=CC=C(C=C3)S(=O)(=O)C)N=CC=C2)CC(=O)O
Standard InChIKey YOPFAMROKXHVCQ-UHFFFAOYSA-N
Standard InChI InChI=1S/C18H18N2O4S/c1-12-16(10-17(21)22)15-4-3-9-19-18(15)20(12)11-13-5-7-14(8-6-13)25(2,23)24/h3-9H,10-11H2,1-2H3,(H,21,22)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

NVP-QAV680 Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

NVP-QAV680 Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of NVP-QAV680

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7901 mL 13.9505 mL 27.901 mL 55.802 mL 69.7525 mL
5 mM 0.558 mL 2.7901 mL 5.5802 mL 11.1604 mL 13.9505 mL
10 mM 0.279 mL 1.3951 mL 2.7901 mL 5.5802 mL 6.9753 mL
50 mM 0.0558 mL 0.279 mL 0.558 mL 1.116 mL 1.3951 mL
100 mM 0.0279 mL 0.1395 mL 0.279 mL 0.558 mL 0.6975 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on NVP-QAV680

Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases.[Pubmed:24021582]

Bioorg Med Chem. 2013 Nov 1;21(21):6582-91.

Optimization of a 7-azaindole-3-acetic acid CRTh2 receptor antagonist chemotype derived from high throughput screening furnished a highly selective compound NVP-QAV680 with low nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro. The molecule exhibited good oral bioavailability in the rat, combined with efficacy in rodent CRTh2-dependent mechanistic and allergic disease models and was suitable for clinical development.

Keywords:

NVP-QAV680,872365-16-7,Natural Products,CRTH2, buy NVP-QAV680 , NVP-QAV680 supplier , purchase NVP-QAV680 , NVP-QAV680 cost , NVP-QAV680 manufacturer , order NVP-QAV680 , high purity NVP-QAV680

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: