Neochebulagic acidCAS# 28196-46-5 |
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| Cas No. | 28196-46-5 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C41H32O28 | M.Wt | 972.67 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Terminalia chebula
| Description | 1. 3,4',5-Trimethoxystilbene exhibits potent antitumor and anti-HCV activities without exhibiting cytotoxicity to human hepatocytes in vitro or in mice livers. 2. 3,4',5-Trimethoxystilbene acts as an inhibitor of tubulin polymerization. 3. 3,4',5-Trimethoxystilbene is a potent small molecule inducer of autophagy in human umbilical vascular endothelial cells (HUVECs) in the presence of serum. 4. 3,4',5-Trimethoxystilbene has anti-inflammatory activity, the ability of it to induce HO-1 expression may provide one of possible mechanisms of its anti-inflammatory action. 5. 3,4',5-Trimethoxystilbene exerts antiangiogenic and vascular-disrupting effects in zebrafish through the downregulation of VEGFR2 and cell-cycle modulation. 6. 3,4',5-Trimethoxystilbene exerts antiallergic and anti-mitotic properties. |
| Targets | HCV | AMPK | mTOR | Calcium Channel | TNF-α | HO-1 | IL Receptor |
Neochebulagic acid Dilution Calculator
Neochebulagic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.0281 mL | 5.1405 mL | 10.281 mL | 20.562 mL | 25.7024 mL |
| 5 mM | 0.2056 mL | 1.0281 mL | 2.0562 mL | 4.1124 mL | 5.1405 mL |
| 10 mM | 0.1028 mL | 0.514 mL | 1.0281 mL | 2.0562 mL | 2.5702 mL |
| 50 mM | 0.0206 mL | 0.1028 mL | 0.2056 mL | 0.4112 mL | 0.514 mL |
| 100 mM | 0.0103 mL | 0.0514 mL | 0.1028 mL | 0.2056 mL | 0.257 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Analysis of hydrolyzable tannins and other phenolic compounds in emblic leafflower (Phyllanthus emblica L.) fruits by high performance liquid chromatography-electrospray ionization mass spectrometry.[Pubmed:22889097]
J Agric Food Chem. 2012 Sep 5;60(35):8672-83.
Phenolic compounds were extracted from dried emblic leafflower (Phyllanthus emblica L.) fruits with methanol and separated by Sephadex LH-20 column chromatography. The raw extracts and fractions were analyzed with HPLC coupled with diode array UV spectroscopy, electrospray ionization mass spectrometry, and tandem mass spectrometry. Mucic acid gallate, mucic acid lactone gallate, monogalloylglucose, gallic acid, digalloylglucose, putranjivain A, galloyl-HHDP-glucose, elaeocarpusin, and chebulagic acid were suggested to be the most abundant compounds in the crude methanol extracts of the fruits. In addition, 144 peaks were detected, of which 67 were tentatively identified mostly as ellagitannins, flavonoids, and simple gallic acid derivatives in the fractions. The results indicated the presence of Neochebulagic acid, isomers of neochebuloyl galloylglucose, chebuloyl neochebuloyl galloylglucose, ellagic acid glycosides, quercetin glycosides, and eriodictyol coumaroyl glycosides in the fruits. The study provides a systematic report of the retention data and characteristics of UV, MS, and MS/MS spectra of the phenolic compounds in the fruits of emblic leafflower. The fruits of two varieties (Ping Dan No 1 and Fruity) from Guangxi Province differed from those of wild Tian Chuan emblic leafflower from Fujian Province in the content and profile of phenolic compounds.
Neochebulagic acid is isolated from Phyllanthus emblica L..
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