Nervosine

CAS# 23179-26-2

Nervosine

2D Structure

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Quality Control of Nervosine

3D structure

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Nervosine

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Chemical Properties of Nervosine

Cas No. 23179-26-2 SDF Download SDF
PubChem ID 185529 Appearance Powder
Formula C36H53NO12 M.Wt 691.81
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(8R)-2,3,5,6,7,8-hexahydro-1H-pyrrolizin-1-yl]methyl 4-[(2R,3R,4S,5S,6R)-3-[(3R,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-bis(3-methylbut-2-enyl)benzoate
SMILES CC(=CCC1=CC(=CC(=C1OC2C(C(C(C(O2)CO)O)O)OC3C(C(C(O3)CO)O)O)CC=C(C)C)C(=O)OCC4CCN5C4CCC5)C
Standard InChIKey LLZLNFVFAZZRDM-NYGIAEFMSA-N
Standard InChI InChI=1S/C36H53NO12/c1-19(2)7-9-21-14-24(34(44)45-18-23-11-13-37-12-5-6-25(23)37)15-22(10-8-20(3)4)32(21)48-36-33(30(42)28(40)26(16-38)47-36)49-35-31(43)29(41)27(17-39)46-35/h7-8,14-15,23,25-31,33,35-36,38-43H,5-6,9-13,16-18H2,1-4H3/t23?,25-,26-,27+,28-,29+,30+,31-,33-,35?,36-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Protocol of Nervosine

Structure Identification
Chinese Chemical Letters, 2016,27(5):757-760.

Three new pyrrolizidine alkaloids derivatives from Liparis nervosa.[Reference: WebLink]


METHODS AND RESULTS:
Three new pyrrolizidine alkaloids, Nervosine VII (1), Nervosine VIII (2) and Nervosine IX (3) were isolated from the whole plant extract of Liparis nervosa. Their structures were elucidated by extensive spectroscopic analyses (including 1D, 2D NMR, and HR-ESI-MS) and chemical methods.
CONCLUSIONS:
Compounds 1–3 were evaluated for their cytotoxic activity against A549, MCF-7and H460 human cancer cell lines.

Nervosine Dilution Calculator

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Nervosine Molarity Calculator

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Preparing Stock Solutions of Nervosine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4455 mL 7.2274 mL 14.4548 mL 28.9097 mL 36.1371 mL
5 mM 0.2891 mL 1.4455 mL 2.891 mL 5.7819 mL 7.2274 mL
10 mM 0.1445 mL 0.7227 mL 1.4455 mL 2.891 mL 3.6137 mL
50 mM 0.0289 mL 0.1445 mL 0.2891 mL 0.5782 mL 0.7227 mL
100 mM 0.0145 mL 0.0723 mL 0.1445 mL 0.2891 mL 0.3614 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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