NuezhenideCAS# 39011-92-2 |
- Specneuzhenide
Catalog No.:BCC9151
CAS No.:449733-84-0
Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 39011-92-2 | SDF | Download SDF |
| PubChem ID | 6440999 | Appearance | Powder |
| Formula | C31H42O17 | M.Wt | 686.7 |
| Type of Compound | Iridoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | methyl (5E,6S)-5-ethylidene-4-[2-oxo-2-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[2-(4-hydroxyphenyl)ethoxy]oxan-2-yl]methoxy]ethyl]-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate | ||
| SMILES | CC=C1C(C(=COC1OC2C(C(C(C(O2)CO)O)O)O)C(=O)OC)CC(=O)OCC3C(C(C(C(O3)OCCC4=CC=C(C=C4)O)O)O)O | ||
| Standard InChIKey | STKUCSFEBXPTAY-YTECAPLWSA-N | ||
| Standard InChI | InChI=1S/C31H42O17/c1-3-16-17(18(28(41)42-2)12-45-29(16)48-31-27(40)24(37)22(35)19(11-32)46-31)10-21(34)44-13-20-23(36)25(38)26(39)30(47-20)43-9-8-14-4-6-15(33)7-5-14/h3-7,12,17,19-20,22-27,29-33,35-40H,8-11,13H2,1-2H3/b16-3+/t17?,19-,20-,22-,23-,24+,25+,26-,27-,29+,30-,31+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect to the seeds of wheat and Chinese cabbage. It significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity. |
| In vitro | A new neuroprotective compound of Ligustrum japonicum leaves.[Pubmed: 16450298 ]Planta Med., 2006, 72(1):62-4.
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| Structure Identification | J Agric Food Chem. 2015 Feb 25;63(7):1990-5.Phenolic profile characterization of Chemlali olive stones by liquid chromatography-ion trap mass spectrometry.[Pubmed: 25650173]
Journal of Huzhou Teachers College, 1997(6):40-8.Studies on the Chemical Constituents of Germinant Inhibitor in the Fruits of Ligustrum Lucidum Ait.[Reference: WebLink]
Nuezhenzi is the fruit of Ligustrum Lucidum Ait. that belongs in Olive Family. Germinant inhibition of the fruits had been discovered in recent years, and this effect can be applicable to solve some problems of agricultural production. But no any domestic or foreign articles have been pub-lished that discussed what is the main inhibitory constituent in the fruits.
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Nuezhenide Dilution Calculator
Nuezhenide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.4562 mL | 7.2812 mL | 14.5624 mL | 29.1248 mL | 36.406 mL |
| 5 mM | 0.2912 mL | 1.4562 mL | 2.9125 mL | 5.825 mL | 7.2812 mL |
| 10 mM | 0.1456 mL | 0.7281 mL | 1.4562 mL | 2.9125 mL | 3.6406 mL |
| 50 mM | 0.0291 mL | 0.1456 mL | 0.2912 mL | 0.5825 mL | 0.7281 mL |
| 100 mM | 0.0146 mL | 0.0728 mL | 0.1456 mL | 0.2912 mL | 0.3641 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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A new neuroprotective compound of Ligustrum japonicum leaves.[Pubmed:16450298]
Planta Med. 2006 Jan;72(1):62-4.
A new secoiridoid glycoside characterized as (8 Z)-Nuezhenide A along with five known glycosides, (8 E)-Nuezhenide, (8 Z)-Nuezhenide, oleoNuezhenide, osmanthuside B and osmanthuside D, were isolated from the n-BuOH fraction of Ligustrum japonicum leaves. All six compounds significantly protected human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.
Phenolic profile characterization of Chemlali olive stones by liquid chromatography-ion trap mass spectrometry.[Pubmed:25650173]
J Agric Food Chem. 2015 Feb 25;63(7):1990-5.
Aqueous methanol extracts of Chemlali olive stones were analyzed by reverse phase high-performance liquid chromatography (HPLC) with diode array detection and mass spectrometry [LC-MS/MS]. Oleoside, oleoside 11-methyl ester, Nuezhenide, oleoside 11-methyloleoside, Nuezhenide 11-methyloleoside, oleuropein, and glycosides of tryosol and hydroxytyrosol glycosides were identified in stones of Chemali olives. The antioxidant activity observed for the extract of the olive stones (IC50 = 13.84 mug/mL, TEAC = 0.436 mM) may be due to the high content of phenolic compounds, of which the main compounds are Nuezhenide (325.78 mg/100g), methoxy derivative of Nuezhenide (132.46 mg/100g), and Nuezhenide-11-methyloleoside (82.91 mg/100g). These results suggest the use of olive stones as sources of natural antioxidants.
