Prasugrel Maleic acidCAS# 389574-20-3 |
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Quality Control & MSDS
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| Cas No. | 389574-20-3 | SDF | Download SDF |
| PubChem ID | 9870150 | Appearance | Powder |
| Formula | C24H24FNO7S | M.Wt | 489.51 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in DMSO | ||
| Chemical Name | (Z)-but-2-enedioic acid;[5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate | ||
| SMILES | CC(=O)OC1=CC2=C(S1)CCN(C2)C(C3=CC=CC=C3F)C(=O)C4CC4.C(=CC(=O)O)C(=O)O | ||
| Standard InChIKey | YFTPSWAPYMNPMX-BTJKTKAUSA-N | ||
| Standard InChI | InChI=1S/C20H20FNO3S.C4H4O4/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;5-3(6)1-2-4(7)8/h2-5,10,13,19H,6-9,11H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1- | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Prasugrel Maleic acid is a platelet inhibitor with IC50 value of 1.8 μM.
Target: P2Y12 receptor
Prasugrel Maleic acid is a novel platelet inhibitor used for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome who are to be managed with PCI [2].
Prasugrel Maleic acid reduces the aggregation (clumping) of platelets by irreversibly binding to P2Y12 receptors. In rat platelets, prasugrel Maleic acid AM inhibited in vitro platelet aggregation induced by ADP (10 μm) with an IC50 value of 1.8 Μm [2].
Clinical indications: Acute coronary syndrome Ischemic heart disease Sickle cell anemia Stroke Vascular occlusive disease
FDA Approved Date: February 2009
Toxicity: Hypertension Headache Hypercholesterolemia/hyperlipidemia Nausea Epistaxis References: | |||||
Prasugrel Maleic acid Dilution Calculator
Prasugrel Maleic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0429 mL | 10.2143 mL | 20.4286 mL | 40.8572 mL | 51.0715 mL |
| 5 mM | 0.4086 mL | 2.0429 mL | 4.0857 mL | 8.1714 mL | 10.2143 mL |
| 10 mM | 0.2043 mL | 1.0214 mL | 2.0429 mL | 4.0857 mL | 5.1071 mL |
| 50 mM | 0.0409 mL | 0.2043 mL | 0.4086 mL | 0.8171 mL | 1.0214 mL |
| 100 mM | 0.0204 mL | 0.1021 mL | 0.2043 mL | 0.4086 mL | 0.5107 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Prasugrel Maleic acid is a platelet inhibitor with IC50 value of 1.8 μM.
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Prasugrel (PCR 4099) Maleic acid is a thienopyridine and prodrug, inhibits platelet function. Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation.
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