Halaminol A

CAS# 389125-56-8

Halaminol A

Catalog No. BCN1788----Order now to get a substantial discount!

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Quality Control of Halaminol A

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Chemical structure

Halaminol A

3D structure

Chemical Properties of Halaminol A

Cas No. 389125-56-8 SDF Download SDF
PubChem ID 10059639 Appearance Oil
Formula C14H29NO M.Wt 227.39
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R)-2-aminotetradec-13-en-3-ol
SMILES CC(C(CCCCCCCCCC=C)O)N
Standard InChIKey KLWPMNOQFSPVII-UONOGXRCSA-N
Standard InChI InChI=1S/C14H29NO/c1-3-4-5-6-7-8-9-10-11-12-14(16)13(2)15/h3,13-14,16H,1,4-12,15H2,2H3/t13-,14+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Halaminol A

The Haliclona n. sp.

Biological Activity of Halaminol A

Description1. Halaminol A and haliclonacyclamine A have similar effects on sponge, polychaete, gastropod and bryozoan larvae, inhibit both settlement and metamorphosis, and prevent fouling and colonisation.
TargetsAntifection

Halaminol A Dilution Calculator

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Halaminol A Molarity Calculator

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Preparing Stock Solutions of Halaminol A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3977 mL 21.9887 mL 43.9773 mL 87.9546 mL 109.9433 mL
5 mM 0.8795 mL 4.3977 mL 8.7955 mL 17.5909 mL 21.9887 mL
10 mM 0.4398 mL 2.1989 mL 4.3977 mL 8.7955 mL 10.9943 mL
50 mM 0.088 mL 0.4398 mL 0.8795 mL 1.7591 mL 2.1989 mL
100 mM 0.044 mL 0.2199 mL 0.4398 mL 0.8795 mL 1.0994 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Halaminol A

Convergent antifouling activities of structurally distinct bioactive compounds synthesized within two sympatric Haliclona demosponges.[Pubmed:18690486]

Mar Biotechnol (NY). 2009 Mar-Apr;11(2):188-98.

A wide range of sessile and sedentary marine invertebrates synthesize secondary metabolites that have potential as industrial antifoulants. These antifoulants tend to differ in structure, even between closely related species. Here, we determine if structurally divergent secondary metabolites produced within two sympatric haliclonid demosponges have similar effects on the larvae of a wide range of benthic competitors and potential fouling metazoans (ascidians, molluscs, bryozoans, polychaetes, and sponges). The sponges Haliclona sp. 628 and sp. 1031 synthesize the tetracyclic alkaloid, haliclonacyclamine A (HA), and the long chain alkyl amino alcohol, Halaminol A (LA), respectively. Despite structural differences, HA and LA have identical effects on phylogenetically disparate ascidian larvae, inducing rapid larval settlement but preventing subsequent metamorphosis at precisely the same stage. HA and LA also have similar effects on sponge, polychaete, gastropod and bryozoan larvae, inhibiting both settlement and metamorphosis. Despite having identical roles in preventing fouling and colonisation, HA and LA differentially affect the physiology of cultured HeLa human cells, indicating they have different molecular targets. From these data, we infer that the secondary metabolites within marine sponges may emerge by varying evolutionary and biosynthetic trajectories that converge on specific ecological roles.

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