P2Y Receptor - GPCR/G protein

Cat.No. Product Name Information

BCC7804 NF 546 NF546 is a selective non-nucleotide P2Y11 agonist with a pEC50 of 6.27. NF546 stimulates release of interleukin-8 from human monocyte-derived dendritic cells. NF 546

BCC7800 MRS 2768 tetrasodium salt

BCC6095 PSB 0739

BCC6153 5-OMe-UDP trisodium salt Potent P2Y<sub>6</sub> agonist

BCC6133 MRS 2957 triethylammonium salt

BCC7624 UTPγS trisodium salt

BCC7603 alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt α,β-Methylene ATP trisodium, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand.

BCC7625 2-ThioUTP tetrasodium salt

BCC7386 MRS 2693 trisodium salt

BCC5685 MRS 2179 tetrasodium salt

BCC6004 AR-C 66096 tetrasodium salt Potent and selective P2Y<sub>12</sub> antagonist

BCC7514 MRS 2690

BCC7785 NF 340 NF 340

BCC4975 Ticagrelor Ticagrelor (AZD6140) is a reversible oral P2Y12 receptor antagonist for the treatment of platelet aggregation.

BCC7570 UDP disodium salt Uridine-5'-diphosphate disodium salt is a potent, selective P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52) and a potent P2Y14 antagonist (pEC50=7.28). Uridine-5'-diphosphate disodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis. UDP disodium salt

BCC5880 MRS 2279

BCC4291 Prasugrel hydrochloride Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and prodrug, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation.

BCC4292 Prasugrel Maleic acid Prasugrel (PCR 4099) Maleic acid is a thienopyridine and prodrug, inhibits platelet function. Prasugrel Maleic acid is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation.

BCC5879 MRS 2365

BCC5794 2-Methylthioadenosine diphosphate trisodium salt

BCC7151 PIT PIT

BCC5881 MRS 2500 tetraammonium salt

BCC4976 MRS 2578 MRS 2578 is a selective and potent P2Y6 receptor antagonist with IC50s of 37 nM (human) and 98 nM (rat). MRS 2578 exhibits insignificant activity at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.

BCC7459 PSB 0474

BCC5370 AZD1283 AZD1283 is a potent antagonist of the P2Y12 receptor with EC50 of 3.0 ug/kg/min, TI >10; with binding IC50 of 11 nM. AZD1283

Products for P2Y Receptor