Home >> Research Area >>GPCR/G protein>>P2Y Receptor>> MRS 2768 tetrasodium salt

MRS 2768 tetrasodium salt

Selective P2Y2 agonist CAS# 1047980-83-5

MRS 2768 tetrasodium salt

Catalog No. BCC7800----Order now to get a substantial discount!

Product Name & Size Price Stock
MRS 2768 tetrasodium salt: 5mg $1783 In Stock
MRS 2768 tetrasodium salt: 10mg Please Inquire In Stock
MRS 2768 tetrasodium salt: 20mg Please Inquire Please Inquire
MRS 2768 tetrasodium salt: 50mg Please Inquire Please Inquire
MRS 2768 tetrasodium salt: 100mg Please Inquire Please Inquire
MRS 2768 tetrasodium salt: 200mg Please Inquire Please Inquire
MRS 2768 tetrasodium salt: 500mg Please Inquire Please Inquire
MRS 2768 tetrasodium salt: 1000mg Please Inquire Please Inquire
Related Products

Quality Control of MRS 2768 tetrasodium salt

Number of papers citing our products

Chemical structure

MRS 2768 tetrasodium salt

3D structure

Chemical Properties of MRS 2768 tetrasodium salt

Cas No. 1047980-83-5 SDF Download SDF
PubChem ID 90488893 Appearance Powder
Formula C15H16N2O18P4Na4 M.Wt 728.14
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in water (supplied pre-dissolved at a concentration of 10mM)
Chemical Name tetrasodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [oxido-[oxido(phenoxy)phosphoryl]oxyphosphoryl] phosphate
SMILES C1=CC=C(C=C1)OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OCC2C(C(C(O2)N3C=CC(=O)NC3=O)O)O.[Na+].[Na+].[Na+].[Na+]
Standard InChIKey ASYFBNZFGLWLNC-YYXHNCPRSA-J
Standard InChI InChI=1S/C15H20N2O18P4.4Na/c18-11-6-7-17(15(21)16-11)14-13(20)12(19)10(31-14)8-30-36(22,23)33-38(26,27)35-39(28,29)34-37(24,25)32-9-4-2-1-3-5-9;;;;/h1-7,10,12-14,19-20H,8H2,(H,22,23)(H,24,25)(H,26,27)(H,28,29)(H,16,18,21);;;;/q;4*+1/p-4/t10-,12-,13-,14-;;;;/m1..../s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Biological Activity of MRS 2768 tetrasodium salt

DescriptionSelective P2Y2 agonist (EC50 = 1.89 μM). Displays no affinity for human P2Y4 or P2Y6 receptors.

MRS 2768 tetrasodium salt Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

MRS 2768 tetrasodium salt Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of MRS 2768 tetrasodium salt

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.3734 mL 6.8668 mL 13.7336 mL 27.4672 mL 34.3341 mL
5 mM 0.2747 mL 1.3734 mL 2.7467 mL 5.4934 mL 6.8668 mL
10 mM 0.1373 mL 0.6867 mL 1.3734 mL 2.7467 mL 3.4334 mL
50 mM 0.0275 mL 0.1373 mL 0.2747 mL 0.5493 mL 0.6867 mL
100 mM 0.0137 mL 0.0687 mL 0.1373 mL 0.2747 mL 0.3433 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on MRS 2768 tetrasodium salt

Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.[Pubmed:18514530]

Bioorg Med Chem. 2008 Jun 15;16(12):6319-32.

The phosphate, uracil, and ribose moieties of uracil nucleotides were varied structurally for evaluation of agonist activity at the human P2Y(2), P2Y(4), and P2Y(6) receptors. The 2-thio modification, found previously to enhance P2Y(2) receptor potency, could be combined with other favorable modifications to produce novel molecules that exhibit high potencies and receptor selectivities. Phosphonomethylene bridges introduced for stability in analogues of UDP, UTP, and uracil dinucleotides markedly reduced potency. Truncation of dinucleotide agonists of the P2Y(2) receptor, in the form of Up(4)-sugars, indicated that a terminal uracil ring is not essential for moderate potency at this receptor and that specific SAR patterns are observed at this distal end of the molecule. Key compounds reported in this study include 9, alpha,beta-methylene-UDP, a P2Y(6) receptor agonist; 30, Up(4)-phenyl ester and 34, Up(4)-[1]glucose, selective P2Y(2) receptor agonists; dihalomethylene phosphonate analogues 16 and 41, selective P2Y(2) receptor agonists; 43, the 2-thio analogue of INS37217 (P(1)-(uridine-5')-P(4)-(2'-deoxycytidine-5')tetraphosphate), a potent and selective P2Y(2) receptor agonist.

Keywords:

MRS 2768 tetrasodium salt,1047980-83-5,Natural Products,P2Y Receptor, buy MRS 2768 tetrasodium salt , MRS 2768 tetrasodium salt supplier , purchase MRS 2768 tetrasodium salt , MRS 2768 tetrasodium salt cost , MRS 2768 tetrasodium salt manufacturer , order MRS 2768 tetrasodium salt , high purity MRS 2768 tetrasodium salt

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: