Panaxyne

CAS# 122855-49-6

Panaxyne

Catalog No. BCN6462----Order now to get a substantial discount!

Product Name & Size Price Stock
Panaxyne: 5mg $828 In Stock
Panaxyne: 10mg Please Inquire In Stock
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Quality Control of Panaxyne

Number of papers citing our products

Chemical structure

Panaxyne

3D structure

Chemical Properties of Panaxyne

Cas No. 122855-49-6 SDF Download SDF
PubChem ID 53440552 Appearance Powder
Formula C14H20O2 M.Wt 220.3
Type of Compound Lipids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name tetradec-13-en-1,3-diyne-6,7-diol
SMILES C=CCCCCCC(C(CC#CC#C)O)O
Standard InChIKey WOVGAQBKTGZPTO-UHFFFAOYSA-N
Standard InChI InChI=1S/C14H20O2/c1-3-5-7-8-10-12-14(16)13(15)11-9-6-4-2/h2-3,13-16H,1,5,7-8,10-12H2
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Panaxyne

The roots of Panax ginseng

Biological Activity of Panaxyne

Description1. Panaxyne shows significant and selective cytotoxicity against SK-OV-3 with ED50 value of 1.40 microM.

Panaxyne Dilution Calculator

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Panaxyne Molarity Calculator

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Preparing Stock Solutions of Panaxyne

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.5393 mL 22.6963 mL 45.3926 mL 90.7853 mL 113.4816 mL
5 mM 0.9079 mL 4.5393 mL 9.0785 mL 18.1571 mL 22.6963 mL
10 mM 0.4539 mL 2.2696 mL 4.5393 mL 9.0785 mL 11.3482 mL
50 mM 0.0908 mL 0.4539 mL 0.9079 mL 1.8157 mL 2.2696 mL
100 mM 0.0454 mL 0.227 mL 0.4539 mL 0.9079 mL 1.1348 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Panaxyne

Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro.[Pubmed:18365683]

Arch Pharm Res. 2008 Feb;31(2):154-9.

Column chromatographic separation of the roots of cultivated-wild ginseng (Jangnoisam) led to the isolation of seven polyacetylenes (1-7). Their structures were determined by spectroscopic methods to be panaxynol (1), ginsenoyne-A (2), panaxydol (3), 10-methoxy heptadeca-1-ene-4, 6-dyne-3, 9-diol (4) (3R, 9R, 10R)-panaxytriol (5), Panaxyne (6), and ginsenoyne-C (7). These compounds were isolated from this source for the first time. The compounds were tested for their cytotoxic activity against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using the SRB method. Panaxydol (3) and Panaxyne (6) showed significant and selective cytotoxicity against SK-OV-3 with ED50 values 2.93 and 1.40 microM, respectively.

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