PanaxyneCAS# 122855-49-6 |
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| Cas No. | 122855-49-6 | SDF | Download SDF |
| PubChem ID | 53440552 | Appearance | Powder |
| Formula | C14H20O2 | M.Wt | 220.3 |
| Type of Compound | Lipids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | tetradec-13-en-1,3-diyne-6,7-diol | ||
| SMILES | C=CCCCCCC(C(CC#CC#C)O)O | ||
| Standard InChIKey | WOVGAQBKTGZPTO-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C14H20O2/c1-3-5-7-8-10-12-14(16)13(15)11-9-6-4-2/h2-3,13-16H,1,5,7-8,10-12H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Panax ginseng
| Description | 1. Panaxyne shows significant and selective cytotoxicity against SK-OV-3 with ED50 value of 1.40 microM. |
Panaxyne Dilution Calculator
Panaxyne Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.5393 mL | 22.6963 mL | 45.3926 mL | 90.7853 mL | 113.4816 mL |
| 5 mM | 0.9079 mL | 4.5393 mL | 9.0785 mL | 18.1571 mL | 22.6963 mL |
| 10 mM | 0.4539 mL | 2.2696 mL | 4.5393 mL | 9.0785 mL | 11.3482 mL |
| 50 mM | 0.0908 mL | 0.4539 mL | 0.9079 mL | 1.8157 mL | 2.2696 mL |
| 100 mM | 0.0454 mL | 0.227 mL | 0.4539 mL | 0.9079 mL | 1.1348 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro.[Pubmed:18365683]
Arch Pharm Res. 2008 Feb;31(2):154-9.
Column chromatographic separation of the roots of cultivated-wild ginseng (Jangnoisam) led to the isolation of seven polyacetylenes (1-7). Their structures were determined by spectroscopic methods to be panaxynol (1), ginsenoyne-A (2), panaxydol (3), 10-methoxy heptadeca-1-ene-4, 6-dyne-3, 9-diol (4) (3R, 9R, 10R)-panaxytriol (5), Panaxyne (6), and ginsenoyne-C (7). These compounds were isolated from this source for the first time. The compounds were tested for their cytotoxic activity against four human cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro using the SRB method. Panaxydol (3) and Panaxyne (6) showed significant and selective cytotoxicity against SK-OV-3 with ED50 values 2.93 and 1.40 microM, respectively.
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