Cefoselis SulfateCAS# 122841-12-7 |
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Quality Control & MSDS
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| Cas No. | 122841-12-7 | SDF | Download SDF |
| PubChem ID | 9830519 | Appearance | Powder |
| Formula | C19H24N8O10S3 | M.Wt | 620.64 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Synonyms | FK-037 | ||
| Solubility | DMSO : 100 mg/mL (161.12 mM; Need ultrasonic) H2O : 14.29 mg/mL (23.02 mM; Need ultrasonic) | ||
| Chemical Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[2-(2-hydroxyethyl)-3-iminopyrazol-1-yl]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;sulfuric acid | ||
| SMILES | CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CN4C=CC(=N)N4CCO)C(=O)O.OS(=O)(=O)O | ||
| Standard InChIKey | LZOLCSVRFKCSEM-ZQCAECPKSA-N | ||
| Standard InChI | InChI=1S/C19H22N8O6S2.H2O4S/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28;1-5(2,3)4/h2-3,8,13,17,20,28H,4-7H2,1H3,(H2,21,22)(H,23,29)(H,31,32);(H2,1,2,3,4)/b20-11?,24-12-;/t13-,17-;/m1./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Cefoselis is a widely used beta-lactam antibiotic.
Target: Antibacterial
Cefoselis, a new parenteral cephalosporin, was active against clinical isolates of both gram-positive and gram-negative aerobic bacteria. The activity of Cefoselis was similar to that of cefpirome and cefepime and generally superior to that of ceftazidime. Cefoselis showed potent antibacterial activity against Hemophilus influenzae and Moraxella catarrhalis.Cefoselis was highly active against MSSA and MSCNS. Cefoselis was poor in the activity against MRSA,MRCNS,PRSP and Enterococcus faecalis,and no activity for Enterococcus faecium. References: | |||||
Cefoselis Sulfate Dilution Calculator
Cefoselis Sulfate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.6112 mL | 8.0562 mL | 16.1124 mL | 32.2248 mL | 40.281 mL |
| 5 mM | 0.3222 mL | 1.6112 mL | 3.2225 mL | 6.445 mL | 8.0562 mL |
| 10 mM | 0.1611 mL | 0.8056 mL | 1.6112 mL | 3.2225 mL | 4.0281 mL |
| 50 mM | 0.0322 mL | 0.1611 mL | 0.3222 mL | 0.6445 mL | 0.8056 mL |
| 100 mM | 0.0161 mL | 0.0806 mL | 0.1611 mL | 0.3222 mL | 0.4028 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cefoselis is a widely used beta-lactam antibiotic.
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Stability studies of cefoselis sulfate in the solid state.[Pubmed:26073113]
J Pharm Biomed Anal. 2015 Oct 10;114:222-6.
The process of degradation was studied by using an HPLC-DAD method. Two degradation products were identified with a hybrid ESI-Q-TOF mass spectrometer. The influence of temperature and relative air humidity (RH) on the stability of Cefoselis Sulfate was investigated. In the solid state at increased RH the degradation of Cefoselis Sulfate was an autocatalytic reaction of the first order with respect to substrate concentration while in dry air was first-order reaction depending on the substrate concentration. The kinetic and thermodynamic parameters of degradation were calculated.
Cefoselis sulfate is a widely used beta-lactam antibiotic.
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